SCHEMBL897607

SCHEMBL897607

CCc1ccc2ccccc2c1C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.55
ALDH1A1 P00352 2/20 0.55
GLA P06280 2/20 0.55
HPGD P15428 2/20 0.55
HSD17B10 Q99714 2/20 0.55
MEN1 O00255 1/20 0.55
CYP1A2 P05177 1/20 0.55
CYP2C19 P33261 1/20 0.55
KMT2A Q03164 1/20 0.55
WDR5 P61964 1/20 0.47
METAP2 P50579 1/20 0.46
METAP1 P53582 1/20 0.46
LDHA P00338 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
NR4A1 P22736 1/20 0.46
NR4A2 P43354 1/20 0.46
NR4A3 Q92570 1/20 0.46
CDC25B P30305 1/20 0.44
P2RX3 P56373 1/20 0.44
ME2 P23368 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL7720474 0.98 KDM4E (0.53) KDM4EALDH1A1GLAHPGDHSD17B10
Ammonia Solution, Strong SCHEMBL7720478 0.98 KDM4E (0.53) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL1696920 0.88 KDM4E (0.50) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL29913819 0.87 KDM4E (0.57) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL27326726 0.87 CNR1 (0.44) KDM4EALDH1A1GLAHPGDHSD17B10
Ammonia Solution, Strong SCHEMBL7717868 0.86 KDM4E (0.49) KDM4EALDH1A1GLAHPGDHSD17B10
Ammonia Solution, Strong SCHEMBL7717870 0.86 KDM4E (0.49) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL3223372 0.85 BID (0.50) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL8335252 0.84 ALDH1A1 (0.55) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL19320910 0.84 KDM4E (0.50) KDM4EALDH1A1GLAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 217 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12565549-B2 Process to prepare a procatalyst for polymerization of olefins SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2026-03-03 US claimed
EP-3519457-B1 PROCESS TO PREPARE PROCATALYST FOR POLYMERIZATION OF OLEFINS SABIC GLOBAL TECHNOLOGIES BV (NL) 2024-06-12 EP claimed
EP-3310822-B1 PROCATALYST FOR POLYMERIZATION OF OLEFINS COMPRISING AN AMINOBENZOATE INTERNAL DONOR AND A 1,3-DIETHER INTERNAL DONOR IN A SPECIFIC RATIO SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-10-11 EP claimed
EP-3519458-B1 PROCESS TO PREPARE PROCATALYST FOR POLYMERIZATION OF OLEFINS SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-08-09 EP claimed
US-20230021046-A1 PROCESS TO PREPARE A PROCATALYST FOR POLYMERIZATION OF OLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2023-01-19 US claimed
EP-4061527-A1 PROCESS TO PREPARE A PROCATALYST FOR POLYMERIZATION OF OLEFINS SABIC Global Technologies B.V. (NL) 2022-09-28 EP claimed
US-11192962-B2 Process to prepare procatalyst for polymerization of olefins SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-12-07 US claimed
US-11117989-B2 Process to prepare procatalyst for polymerization of olefins SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-09-14 US claimed
WO-2021099134-A1 PROCESS TO PREPARE A PROCATALYST FOR POLYMERIZATION OF OLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-05-27 WO claimed
US-10882924-B2 Procatalyst for polymerization of olefins SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-01-05 US claimed
EP-3519457-A1 PROCESS TO PREPARE PROCATALYST FOR POLYMERIZATION OF OLEFINS SABIC Global Technologies B.V. (NL) 2019-08-07 EP claimed
EP-3519458-A1 PROCESS TO PREPARE PROCATALYST FOR POLYMERIZATION OF OLEFINS SABIC Global Technologies B.V. (NL) 2019-08-07 EP claimed
US-20190225716-A1 PROCATALYST FOR POLYMERIZATION OF OLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-07-25 US claimed
US-20190225718-A1 PROCATALYST FOR POLYMERIZATION OF OLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2019-07-25 US claimed
EP-3310822-A1 PROCATALYST FOR POLYMERIZATION OF OLEFINS COMPRISING AN AMINOBENZOATE INTERNAL DONOR AND A 1,3-DIETHER INTERNAL DONOR IN A SPECIFIC RATIO SABIC Global Technologies B.V. (NL) 2018-04-25 EP claimed
WO-2018059750-A1 PROCESS TO PREPARE PROCATALYST FOR POLYMERIZATION OF OLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-04-05 WO claimed
WO-2018059955-A1 PROCESS TO PREPARE PROCATALYST FOR POLYMERIZATION OF OLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-04-05 WO claimed
WO-2016203017-A1 PROCATALYST FOR POLYMERIZATION OF OLEFINS COMPRISING AN AMINOBENZOATE INTERNAL DONOR AND A 1,3-DIETHER INTERNAL DONOR IN A SPECIFIC RATIO SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2016-12-22 WO claimed
US-4187196-A REACTING HALOGENATED TITANIUM COMPOUND WITH MAGNESIUM OR MANGANESE DIHALIDE MONTEDISON S.P.A. (IT) 1980-02-05 US claimed
US-4107414-A Process for the stereoregular polymerization of alpha olefins MONTECATINI EDISON S.P.A. (IT) 1978-08-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10882924-B2 Procatalyst for polymerization of olefins PPOX, POR, OGFOD1 KDM4E 2111/4885ALDH1A1 352/4885GLA 2488/4885
US-20190225716-A1 PROCATALYST FOR POLYMERIZATION OF OLEFINS PPOX, POR, OGFOD1 KDM4E 2111/4885ALDH1A1 352/4885GLA 2488/4885
US-20190225718-A1 PROCATALYST FOR POLYMERIZATION OF OLEFINS PPOX, POR, SCO2 KDM4E 1993/4885ALDH1A1 308/4885GLA 2529/4885
US-12565549-B2 Process to prepare a procatalyst for polymerization of olefins AGL, PI4K2A, PI4K2B KDM4E 2542/4885ALDH1A1 3253/4885GLA 1196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.