Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL7720474

CCc1ccc2ccccc2c1C(=O)O.N

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.53
ALDH1A1 P00352 2/20 0.53
GLA P06280 2/20 0.53
HPGD P15428 2/20 0.53
HSD17B10 Q99714 2/20 0.53
MEN1 O00255 1/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2C19 P33261 1/20 0.53
KMT2A Q03164 1/20 0.53
WDR5 P61964 1/20 0.46
METAP2 P50579 1/20 0.45
METAP1 P53582 1/20 0.45
LDHA P00338 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
NR4A1 P22736 1/20 0.44
NR4A2 P43354 1/20 0.44
NR4A3 Q92570 1/20 0.44
P2RX3 P56373 1/20 0.43
CDC25B P30305 1/20 0.43
ME2 P23368 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL7720478 1.00 KDM4E (0.53) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL897607 0.98 KDM4E (0.55) KDM4EALDH1A1GLAHPGDHSD17B10
Ammonia Solution, Strong SCHEMBL7717868 0.88 KDM4E (0.49) KDM4EALDH1A1GLAHPGDHSD17B10
Ammonia Solution, Strong SCHEMBL7717870 0.88 KDM4E (0.49) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL1696920 0.86 KDM4E (0.50) KDM4EALDH1A1GLAHPGDHSD17B10
Ammonia Solution, Strong SCHEMBL7713405 0.85 BID (0.49) KDM4EALDH1A1GLAHPGDHSD17B10
Ammonia Solution, Strong SCHEMBL7713404 0.85 BID (0.49) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL29913819 0.85 KDM4E (0.57) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL27326726 0.85 CNR1 (0.44) KDM4EALDH1A1GLAHPGDHSD17B10
SCHEMBL3223372 0.83 BID (0.50) KDM4EALDH1A1GLAHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6383275-B1 MIXTURE OF WATER, COLORANT AD WATER SOLUBLE DISCOLORATION INHIBITOR XEROX CORPORATION 2002-05-07 US claimed
US-6383275-B1 MIXTURE OF WATER, COLORANT AD WATER SOLUBLE DISCOLORATION INHIBITOR XEROX CORPORATION 2002-05-07 US disclosed