Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | RAB7A | P51149 | 1/20 | 0.39 |
| ▸ | SLC34A2 | O95436 | 2/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 7/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 7/20 | 0.38 |
| ▸ | CACNA1I | Q9P0X4 | 7/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | FABP4 | P15090 | 2/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19325531 | 0.92 | RAB7A (0.46) | PDE4BPDE4DRAB7ASLC34A2CACNA1G | |
| SCHEMBL19320875 | 0.91 | CACNA1G (0.47) | PDE4BPDE4DRAB7ASLC34A2CACNA1G | |
| SCHEMBL19326200 | 0.88 | CNR2 (0.41) | FABP4FABP5HPGDCNR1CNR2 | |
| SCHEMBL19326182 | 0.83 | RAB7A (0.41) | RAB7ASLC34A2CACNA1GCACNA1HCACNA1I | |
| SCHEMBL19325792 | 0.82 | MAPT (0.44) | ALDH1A1HPGDSMN1; SMN2LMNAHTT | |
| SCHEMBL19320826 | 0.82 | CACNA1G (0.47) | RAB7ASLC34A2CACNA1GCACNA1HCACNA1I | |
| SCHEMBL19325604 | 0.81 | MEN1 (0.46) | ALDH1A1HPGDSMN1; SMN2LMNAHTT | |
| SCHEMBL19325607 | 0.81 | MEN1 (0.46) | ALDH1A1HPGDSMN1; SMN2LMNAHTT | |
| SCHEMBL19326147 | 0.81 | CNR2 (0.34) | RAB7ACNR1CNR2 | |
| SCHEMBL19325537 | 0.81 | CNR2 (0.36) | RAB7ACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170253607-A1 | LONG-ACTING HIV PROTEASE INHIBITOR | SHIONOGI & CO., LTD. (JP) | 2017-09-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170253607-A1 | LONG-ACTING HIV PROTEASE INHIBITOR | CPN1, HAT1, PRSS1 | PDE4B 4744/4885PDE4D 4818/4885RAB7A 1008/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.