SCHEMBL19326923

SCHEMBL19326923

C[C@@H]1OC(CO)[C@@H](ON)C(O)C1N

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.33
▸ AMY1A P0DUB6 1/20 0.33
▸ LRAT O95237 1/20 0.33
▸ TRPV1 Q8NER1 1/20 0.33
▸ TSHR P16473 2/20 0.32
▸ HSD17B10 Q99714 1/20 0.32
▸ LGALS8 O00214 1/20 0.32
▸ GJA1 P17302 1/20 0.31
▸ GJB2 P29033 1/20 0.31
▸ CYP2C9 P11712 1/20 0.31
▸ KMT2A Q03164 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ LMNA P02545 1/20 0.31
▸ OGA O60502 1/20 0.31
▸ KDM4E B2RXH2 1/20 0.31
▸ ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13563735 0.86 OGA (0.39) MEN1AMY1ALRATTRPV1TSHR
SCHEMBL21122324 0.86 OGA (0.39) MEN1AMY1ALRATTRPV1TSHR
SCHEMBL21530603 0.86 OGA (0.39) MEN1AMY1ALRATTRPV1TSHR
SCHEMBL19902013 0.86 OGA (0.39) MEN1AMY1ALRATTRPV1TSHR
SCHEMBL11915783 0.86 OGA (0.39) MEN1AMY1ALRATTRPV1TSHR
SCHEMBL19902050 0.81 MEN1 (0.34) MEN1LRATTRPV1TSHRHSD17B10
SCHEMBL19859960 0.81 L3MBTL1 (0.36) MEN1AMY1ALRATTRPV1TSHR
SCHEMBL20695753 0.81 LGALS1 (0.39) MEN1TSHRLGALS8GJA1GJB2
SCHEMBL18805882 0.81 LGALS1 (0.39) MEN1TSHRLGALS8GJA1GJB2
SCHEMBL18805911 0.81 LGALS1 (0.39) MEN1TSHRLGALS8GJA1GJB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3185901-B1 COMPOUND AND METHOD PCI BIOTECH AS (NO) 2023-10-04 — — EP disclosed
US-20170252441-A1 COMPOUND AND METHOD PCI BIOTECH AS (NO) 2017-09-07 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170252441-A1 COMPOUND AND METHOD CSF3R, IL2, IL5 MEN1 1170/4885AMY1A 4333/4885LRAT 2062/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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