Phenanthroline

Phenanthroline

SCHEMBL19327240

Oc1cccc2cccnc12.c1cnc2c(c1)ccc1cccnc12

nearest known ligand 0.91

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.91
MMP2 P08253 2/20 0.91
METAP2 P50579 2/20 0.91
CHRM1 P11229 1/20 0.91
COMT P21964 1/20 0.91
ADRA1A P35348 1/20 0.91
METAP1 P53582 1/20 0.91
HDAC8 Q9BY41 1/20 0.91
KDM4E B2RXH2 6/20 0.75
ALOX12 P18054 4/20 0.75
LMNA P02545 3/20 0.70
CCR1 P32246 3/20 0.70
CCR5 P51681 3/20 0.70
CCR8 P51685 3/20 0.70
TP53 P04637 2/20 0.70
ALOX15 P16050 2/20 0.70
HTT P42858 2/20 0.70
SMN1; SMN2 Q16637 2/20 0.70
TDP1 Q9NUW8 2/20 0.70
CYP3A4 P08684 2/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxyquinoline SCHEMBL253313 0.96 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL29365411 0.96 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL29716519 0.96 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL37189 0.96 TSHR (1.00) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL23522696 0.93 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL21465312 0.93 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL22467701 0.93 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL21875199 0.93 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL21195162 0.93 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT
Oxyquinoline SCHEMBL20703753 0.93 TSHR (0.95) TSHRMMP2METAP2CHRM1COMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170263871-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2017-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170263871-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE OR10J3, RPS10, OR51E2 TSHR 3010/4885MMP2 3970/4885METAP2 4169/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.