Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 14/20 | 0.52 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19328543 | 0.88 | PTGFR (0.51) | PTGFRDHODH | |
| SCHEMBL19328470 | 0.87 | PTGFR (0.52) | PTGFRDHODH | |
| SCHEMBL19351222 | 0.84 | PTGFR (0.55) | PTGFRDHODHNAMPT | |
| SCHEMBL17593597 | 0.80 | PTGFR (0.64) | PTGFRDHODHALDH1A1GAACYP2C9 | |
| SCHEMBL19328500 | 0.77 | PTGFR (0.52) | PTGFRDHODHALDH1A1GAACYP2C9 | |
| SCHEMBL19328453 | 0.76 | DHODH (0.62) | PTGFRDHODHALDH1A1CYP2C9 | |
| SCHEMBL19328541 | 0.75 | PTGFR (0.56) | PTGFR | |
| SCHEMBL19328515 | 0.74 | PTGFR (0.53) | PTGFRDHODH | |
| SCHEMBL19328548 | 0.74 | DHODH (0.64) | PTGFRDHODH | |
| SCHEMBL5000164 | 0.74 | DHODH (0.60) | DHODHCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10479765-B2 | Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-11-19 | — | — | US | disclosed |
| US-10479765-B2 | Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-11-19 | — | — | US | disclosed |
| US-10189788-B2 | Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-01-29 | — | — | US | disclosed |
| US-10189788-B2 | Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-01-29 | — | — | US | disclosed |
| US-20190002409-A1 | SUBSTITUTED N,2-DIARYLQUINOLINE-4-CARBOXAMIDES AND THE USE THEREOF AS ANTI-INFLAMMATORY AGENTS | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2019-01-03 | — | — | US | disclosed |
| US-20170260140-A1 | SUBSTITUTED N,2-DIARYLQUINOLINE-4-CARBOXAMIDES AND THE USE THEREOF AS ANTI-INFLAMMATORY AGENTS | Bayer Pharma Aktiengesekkschaft (DE) | 2017-09-14 | — | — | US | disclosed |
| US-20170260140-A1 | SUBSTITUTED N,2-DIARYLQUINOLINE-4-CARBOXAMIDES AND THE USE THEREOF AS ANTI-INFLAMMATORY AGENTS | Bayer Pharma Aktiengesekkschaft (DE) | 2017-09-14 | — | — | US | disclosed |
| US-20170260140-A1 | SUBSTITUTED N,2-DIARYLQUINOLINE-4-CARBOXAMIDES AND THE USE THEREOF AS ANTI-INFLAMMATORY AGENTS | Bayer Pharma Aktiengesekkschaft (DE) | 2017-09-14 | — | — | US | disclosed |
| WO-2017153234-A1 | SUBSTITUTED N-CYCLO-2-ARYL-QUINOLINE-4-CARBOXAMIDES AND USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2017-09-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10479765-B2 | Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents | AADAC, NFKBIA, NOD2 | PTGFR 749/4885DHODH 1976/4885ALDH1A1 1598/4885 |
| US-20170260140-A1 | SUBSTITUTED N,2-DIARYLQUINOLINE-4-CARBOXAMIDES AND THE USE THEREOF AS ANTI-INFLAMMATORY AGENTS | AADAC, NFKBIA, NOD2 | PTGFR 749/4885DHODH 1976/4885ALDH1A1 1598/4885 |
| US-20190002409-A1 | SUBSTITUTED N,2-DIARYLQUINOLINE-4-CARBOXAMIDES AND THE USE THEREOF AS ANTI-INFLAMMATORY AGENTS | AADAC, NFKBIA, NOD2 | PTGFR 749/4885DHODH 1976/4885ALDH1A1 1598/4885 |
| US-10189788-B2 | Substituted N,2-diarylquinoline-4-carboxamides and the use thereof as anti-inflammatory agents | AADAC, NFKBIA, NOD2 | PTGFR 749/4885DHODH 1976/4885ALDH1A1 1598/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.