Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 9/20 | 0.39 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27758252 | 0.76 | HCAR2 (0.44) | HCAR2HCAR3DPP4HTTALDH1A1 | |
| SCHEMBL7470965 | 0.74 | HCAR2 (0.39) | HCAR2HCAR3PTPN1PTPN11MAPK1 | |
| SCHEMBL22637869 | 0.74 | PDE4D (0.38) | HCAR2HCAR3MAPK1 | |
| SCHEMBL9218944 | 0.72 | HCAR2 (0.43) | HCAR2HCAR3PTPN1PTPN11ALPL | |
| SCHEMBL21393 | 0.72 | HCAR2 (0.37) | HCAR2HCAR3PTPN1PTPN11ALPL | |
| SCHEMBL17709538 | 0.72 | — | — | |
| SCHEMBL19188 | 0.71 | HCAR2 (0.45) | HCAR2HCAR3PTPN1PTPN11MAPK1 | |
| SCHEMBL28240648 | 0.70 | HCAR2 (0.30) | HCAR2 | |
| SCHEMBL3949940 | 0.68 | HCAR2 (0.45) | HCAR2HCAR3ALPLHTTALDH1A1 | |
| SCHEMBL4650593 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025469-A1 | IMPROVED PROCESS FOR THE PREPARATION OF ESTERS OF 1-H-PYRAZOLE-4-CARBOXYLIC ACIDS | SOLVAY SA (BE) | 2012-03-01 | — | — | WO | disclosed |