Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 7/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.30 |
| ▸ | ALPL | P05186 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7470965 | 0.88 | HCAR2 (0.39) | HCAR2DPP4HCAR3DPP8DPP9 | |
| SCHEMBL28779338 | 0.79 | HCAR2 (0.47) | HCAR2DPP4HCAR3 | |
| SCHEMBL28351122 | 0.76 | PDE4D (0.36) | HCAR2 | |
| SCHEMBL9218944 | 0.73 | HCAR2 (0.43) | HCAR2DPP4HCAR3DPP8DPP9 | |
| SCHEMBL20911 | 0.73 | HCAR2 (0.43) | HCAR2HCAR3PTPN1PTPN11 | |
| SCHEMBL19329 | 0.72 | HCAR2 (0.39) | HCAR2DPP4HCAR3DPP8DPP9 | |
| SCHEMBL15165958 | 0.70 | — | — | |
| SCHEMBL28350977 | 0.69 | HCAR2 (0.38) | HCAR2 | |
| SCHEMBL17294915 | 0.67 | HCAR2 (0.42) | HCAR2HCAR3ALPL | |
| SCHEMBL27737479 | 0.67 | HCAR2 (0.46) | HCAR2DPP4HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012025469-A1 | IMPROVED PROCESS FOR THE PREPARATION OF ESTERS OF 1-H-PYRAZOLE-4-CARBOXYLIC ACIDS | SOLVAY SA (BE) | 2012-03-01 | — | — | WO | disclosed |