Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 9/20 | 0.43 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27737815 | 0.77 | HCAR2 (0.54) | HCAR2HCAR3DPP4KMT2AALDH1A1 | |
| SCHEMBL21393 | 0.73 | HCAR2 (0.37) | HCAR2HCAR3PTPN1PTPN11ALPL | |
| SCHEMBL19329 | 0.72 | HCAR2 (0.39) | HCAR2HCAR3PTPN1PTPN11ALPL | |
| SCHEMBL7470965 | 0.72 | HCAR2 (0.39) | HCAR2HCAR3PTPN1PTPN11ALPL | |
| SCHEMBL27737480 | 0.72 | HCAR2 (0.49) | HCAR2HCAR3ALDH1A1 | |
| SCHEMBL17478590 | 0.71 | HCAR2 (0.51) | HCAR2 | |
| SCHEMBL27737630 | 0.71 | HCAR2 (0.48) | HCAR2HCAR3DPP4ALDH1A1TTR | |
| SCHEMBL11203864 | 0.70 | HCAR2 (0.44) | HCAR2HCAR3ALPLKMT2ATTR | |
| SCHEMBL17294915 | 0.70 | HCAR2 (0.42) | HCAR2HCAR3ALPLKMT2AHTT | |
| SCHEMBL11210298 | 0.70 | HCAR2 (0.41) | HCAR2HCAR3TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0644879-A1 | HERBICIDAL PYRAZOLE-(THIO)-CARBOXAMIDES | RHONE POULENC AGRICULTURE LTD. (GB) | 1995-03-29 | — | — | EP | disclosed |