Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA6 | P23280 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329689 | 0.83 | IKBKB (0.41) | ALDH1A1CA1CA2CA12CA3 | |
| SCHEMBL11529037 | 0.83 | GABRA1 (0.54) | ALDH1A1GABRA1GABRB1CA1CA2 | |
| SCHEMBL19329492 | 0.79 | IKBKB (0.37) | ALDH1A1CA1CA2GAACA12 | |
| SCHEMBL19329516 | 0.77 | CA1 (0.42) | CA1CA2CA12CA3CA4 | |
| SCHEMBL19329493 | 0.76 | IKBKB (0.35) | ALDH1A1CA1CA2CA12CA3 | |
| SCHEMBL19329456 | 0.76 | ERN1 (0.40) | CA1CA2CA12CA3CA4 | |
| SCHEMBL5341709 | 0.75 | GABRA1 (0.55) | ALDH1A1GABRA1GABRB1CA1CA2 | |
| SCHEMBL19329459 | 0.72 | IKBKB (0.35) | CA1CA2CA12CA3CA4 | |
| SCHEMBL15840104 | 0.70 | FABP3 (0.35) | ALDH1A1GABRA1GABRB1CA1CA2 | |
| SCHEMBL6270142 | 0.68 | ALDH1A1 (0.48) | ALDH1A1CA1CA2GAACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017153952-A1 | 5-SULFAMOYL-2-HYDROXYBENZAMIDE DERIVATIVES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-09-14 | — | — | WO | disclosed |