Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.40 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.40 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19329691 | 0.89 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1KDM4EHSD17B10CASP6 | |
| SCHEMBL19329342 | 0.78 | CA1 (0.60) | SMN1; SMN2ALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL19329385 | 0.78 | ALDH1A1 (0.56) | SMN1; SMN2ALDH1A1KDM4EHSD17B10CASP6 | |
| SCHEMBL19329700 | 0.78 | CASP1 (0.46) | SMN1; SMN2ALDH1A1KDM4EHSD17B10CASP6 | |
| SCHEMBL19329542 | 0.77 | CA1 (0.56) | SMN1; SMN2ALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL19329561 | 0.76 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1KDM4EHSD17B10CASP6 | |
| SCHEMBL19329415 | 0.76 | ALDH1A1 (0.60) | SMN1; SMN2ALDH1A1KDM4EHSD17B10MEN1 | |
| SCHEMBL19329446 | 0.76 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1KDM4EHSD17B10CASP6 | |
| SCHEMBL19329474 | 0.76 | ALDH1A1 (0.57) | SMN1; SMN2ALDH1A1KDM4EHSD17B10CASP6 | |
| SCHEMBL19329824 | 0.75 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1KDM4EHSD17B10CASP6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017153952-A1 | 5-SULFAMOYL-2-HYDROXYBENZAMIDE DERIVATIVES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-09-14 | — | — | WO | claimed |
| WO-2017153952-A1 | 5-SULFAMOYL-2-HYDROXYBENZAMIDE DERIVATIVES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-09-14 | — | — | WO | disclosed |