Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | PKM | P14618 | 1/20 | 0.69 |
| ▸ | AR | P10275 | 8/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.60 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ACLY | P53396 | 1/20 | 0.53 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5375202 | 0.91 | MEN1 (0.78) | MEN1KMT2APKMARPOLB | |
| SCHEMBL19329721 | 0.85 | MCL1 (0.63) | MEN1KMT2APGRSMN1; SMN2KDM4E | |
| SCHEMBL19329415 | 0.84 | ALDH1A1 (0.60) | MEN1KMT2APKMPOLBSMN1; SMN2 | |
| SCHEMBL5371903 | 0.81 | MEN1 (0.77) | MEN1KMT2APKMARPOLB | |
| SCHEMBL5380382 | 0.81 | MEN1 (0.77) | MEN1KMT2APKMARPOLB | |
| SCHEMBL19329343 | 0.81 | SMN1; SMN2 (0.58) | MEN1KMT2APKMARPOLB | |
| SCHEMBL19329385 | 0.81 | ALDH1A1 (0.56) | MEN1KMT2APKMARPOLB | |
| SCHEMBL19329631 | 0.80 | POLB (0.64) | MEN1KMT2APKMPOLBPGR | |
| SCHEMBL5373189 | 0.80 | MEN1 (0.77) | MEN1KMT2APKMARPOLB | |
| SCHEMBL5378751 | 0.79 | MEN1 (0.72) | MEN1KMT2APKMARPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017153952-A1 | 5-SULFAMOYL-2-HYDROXYBENZAMIDE DERIVATIVES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-09-14 | — | — | WO | claimed |
| WO-2017153952-A1 | 5-SULFAMOYL-2-HYDROXYBENZAMIDE DERIVATIVES | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-09-14 | — | — | WO | disclosed |