Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29723114 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2CA12CA1CA2CA3 | |
| SCHEMBL14128389 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2CA12CA1CA2CA3 | |
| SCHEMBL2474533 | 0.80 | ACHE (0.46) | KDM4EGLAACHEMAPTGAA | |
| SCHEMBL20643007 | 0.79 | SMN1; SMN2 (0.38) | KDM4EGLASMN1; SMN2CA12CA1 | |
| SCHEMBL14236172 | 0.78 | SMN1; SMN2 (0.40) | KDM4ESMN1; SMN2CA12CA1CA2 | |
| SCHEMBL13858075 | 0.76 | KDM4E (0.39) | KDM4EGLASMN1; SMN2GAAALDH1A1 | |
| SCHEMBL19124079 | 0.71 | GAA (0.42) | KDM4ESMN1; SMN2AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL5318231 | 0.71 | SMN1; SMN2 (0.45) | KDM4EGLASMN1; SMN2ACHE | |
| SCHEMBL28439923 | 0.71 | KDM4E (0.44) | KDM4EGLACA12CA1CA2 | |
| SCHEMBL2481705 | 0.70 | ALDH1A1 (0.44) | KDM4EMAPTGAAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017155816-A1 | QUINAZOLINE COMPOUNDS USEFUL AS M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | MERCK SHARP & DOHME CORP. (US) | 2017-09-14 | — | — | WO | disclosed |