SCHEMBL1933085

SCHEMBL1933085

CSCC[C@H](N)C(=O)OC(=O)[C@@H](N)CS

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.47
ENPEP Q07075 1/20 0.47
RNPEP Q9H4A4 1/20 0.40
FNTA P49354 8/20 0.39
FNTB P49356 8/20 0.39
PGGT1B P53609 2/20 0.39
PTGS1 P23219 1/20 0.38
SLC7A11 Q9UPY5 1/20 0.38
METAP2 P50579 1/20 0.36
METAP1 P53582 1/20 0.36
MARS1 P56192 5/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5617582 0.91 RNPEP (0.42) ANPEPENPEPRNPEPMETAP2METAP1
SCHEMBL162031 0.91 RNPEP (0.42) ANPEPENPEPRNPEPMETAP2METAP1
SCHEMBL6045793 0.91 RNPEP (0.42) ANPEPENPEPRNPEPMETAP2METAP1
SCHEMBL20996747 0.91 RNPEP (0.42) ANPEPENPEPRNPEPMETAP2METAP1
SCHEMBL2418306 0.89 ANPEP (0.42) ANPEPENPEPRNPEPFNTAFNTB
SCHEMBL11531701 0.84 RNPEP (0.37) ANPEPENPEPRNPEPMETAP2METAP1
SCHEMBL7263576 0.84 RNPEP (0.37) ANPEPENPEPRNPEPMETAP2METAP1
SCHEMBL2804079 0.84 METAP2 (0.40) ANPEPENPEPRNPEPMETAP2METAP1
SCHEMBL28729561 0.84 METAP2 (0.43) ANPEPENPEPRNPEPMETAP2METAP1
SCHEMBL6019778 0.84 RNPEP (0.37) ANPEPENPEPRNPEPMETAP2METAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019118370-A1 COMPOSITIONS, METHODS, AND SYSTEMS FOR PRODUCING FLOCCULENT MATERIALS FOR SPECIAL EFFECTS XOTRAMORPHIC, LLC (US) 2019-06-20 WO claimed
CN-1315532-C Compound lysoamidase spray agent and preparing method SHANGHAI NEW MEDICINE RES AND (CN) 2007-05-16 CN claimed
CN-1616092-A Compound lysoamidase spray agent and preparing method SHANGHAI NEW MEDICINE RES AND (CN) 2005-05-18 CN claimed
WO-2004035764-A2 PROTEIN SYNTHESIS WITH TANDEMLY ACTIVATED tRNAs UNIVERSITY OF VIRGINIA PATENT FOUNDATION (US) 2004-04-29 WO claimed
US-20040002542-A1 Succinoylamino hydroxyethylamino sulfonyl urea derivatives useful as retroviral protease inhibitors G.D. SEARLE & CO. 2004-01-01 US claimed
US-20020198378-A1 Succinoylamino hydroxyethylamino sulfonyl urea derivatives useful as retroviral protease inhibitors G.D. SEARLE & CO. 2002-12-26 US claimed
US-5602119-A TREATMENT OF HIV AND AIDS G. D. SEARLE & CO. 1997-02-11 US claimed
EP-0666841-B1 SUCCINOYLAMINO HYDROXYETHYLAMINO SULFAMIC ACID DERIVATIVES USEFUL AS RETROVIRAL PROTEASE INHIBITORS SEARLE & CO (US) 1997-01-22 EP claimed
EP-0666841-A1 SUCCINOYLAMINO HYDROXYETHYLAMINO SULFAMIC ACID DERIVATIVES USEFUL AS RETROVIRAL PROTEASE INHIBITORS. SEARLE & CO (US) 1995-08-16 EP claimed
WO-1994010133-A1 SUCCINOYLAMINO HYDROXYETHYLAMINO SULFAMIC ACID DERIVATIVES USEFUL AS RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1994-05-11 WO claimed
US-5151521-A 1-aminoethyl phosphonic acid derivatives MERCK & CO., INC. (US) 1992-09-29 US claimed
EP-0175871-B1 PROCESS FOR IMPROVING OR MODIFYING THE TASTE AND AROMA OF CITRUS FRUIT COMPOSITIONS FIRMENICH SA (CH) 1988-03-23 EP claimed
EP-0175871-A1 Process for improving or modifying the taste and aroma of citrus fruit compositions FIRMENICH SA (CH) 1986-04-02 EP claimed
WO-2024081864-A1 INHIBITORS OF NT5C2 AND USES THEREOF NEW YORK UNIVERSITY (US) 2024-04-18 WO disclosed
WO-2024076610-A2 INHIBITORS OF SPNS2 AND USES THEREOF NEW YORK UNIVERSITY (US) 2024-04-11 WO disclosed
CN-117604091-A Use of a biomarker detection product in the preparation of a product for aiding in the diagnosis, diagnosis or prognosis of a neural tube abnormality 首都儿科研究所 2024-02-27 CN disclosed
WO-1994010133-A1 SUCCINOYLAMINO HYDROXYETHYLAMINO SULFAMIC ACID DERIVATIVES USEFUL AS RETROVIRAL PROTEASE INHIBITORS G.D. SEARLE & CO. (US) 1994-05-11 WO disclosed
EP-0547065-A4 MELANIN PRODUCTION BY TRANSFORMED MICROORGANISMS 1993-09-15 EP disclosed
EP-0547065-A1 MELANIN PRODUCTION BY TRANSFORMED MICROORGANISMS Biosource Technologies, Inc. (US) 1993-06-23 EP disclosed
WO-1992000373-A1 MELANIN PRODUCTION BY TRANSFORMED MICROORGANISMS BIOSOURCE GENETICS CORPORATION (CA) 1992-01-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020198378-A1 Succinoylamino hydroxyethylamino sulfonyl urea derivatives useful as retroviral protease inhibitors SUMO1, CHUK, SENP1 ANPEP 60/4885ENPEP 88/4885RNPEP 121/4885
US-20040002542-A1 Succinoylamino hydroxyethylamino sulfonyl urea derivatives useful as retroviral protease inhibitors SUMO1, CHUK, SENP1 ANPEP 60/4885ENPEP 88/4885RNPEP 121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.