Fenthion

Fenthion

SCHEMBL1933208

CCOP(=S)(OCC)Oc1ccc(SC)c(C)c1.COP(=S)(OC)Oc1ccc(SC)c(C)c1

nearest known ligand 0.81

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.81
CYP3A4 P08684 7/20 0.81
TSHR P16473 5/20 0.81
HSD17B10 Q99714 5/20 0.81
HPGD P15428 2/20 0.55
TDP1 Q9NUW8 4/20 0.44
KDM4E B2RXH2 3/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA3 P07451 1/20 0.44
CA4 P22748 1/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA9 Q16790 1/20 0.44
CA13 Q8N1Q1 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
MAPK1 P28482 3/20 0.42
MAPT P10636 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL120468 0.94 ALDH1A1 (0.70) ALDH1A1CYP3A4TSHRHSD17B10HPGD
Fenthion SCHEMBL29441335 0.90 ALDH1A1 (1.00) ALDH1A1CYP3A4TSHRHSD17B10HPGD
Fenthion SCHEMBL6739014 0.90 ALDH1A1 (1.00) ALDH1A1CYP3A4TSHRHSD17B10HPGD
Fenthion SCHEMBL26907 0.90 ALDH1A1 (1.00) ALDH1A1CYP3A4TSHRHSD17B10HPGD
Fenthion SCHEMBL28673475 0.87 ALDH1A1 (0.94) ALDH1A1CYP3A4TSHRHSD17B10HPGD
Chlorpyrifos SCHEMBL9300722 0.85 ALDH1A1 (0.61) ALDH1A1CYP3A4TSHRHSD17B10HPGD
Fenthion SCHEMBL8576669 0.84 ALDH1A1 (0.64) ALDH1A1CYP3A4TSHRHSD17B10HPGD
Dimpylate SCHEMBL9668523 0.84 ALDH1A1 (0.64) ALDH1A1CYP3A4TSHRHSD17B10HPGD
Fenthion SCHEMBL5269859 0.83 ALDH1A1 (0.56) ALDH1A1CYP3A4TSHRHSD17B10HPGD
SCHEMBL11671264 0.81 ALDH1A1 (0.58) ALDH1A1CYP3A4TSHRHSD17B10HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130203595-A1 STABLE MIXTURES AND RELATED METHODS SYNGENTA CROP PROTECTION LLC (US) 2013-08-08 US disclosed
EP-2504065-A1 STABLE MIXTURES AND RELATED METHODS Syngenta Participations AG (CH) 2012-10-03 EP disclosed
WO-2011066362-A1 STABLE MIXTURES AND RELATED METHODS SYNGENTA PARTICIPATIONS AG (CH) 2011-06-03 WO disclosed