Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.61 |
| ▸ | TSHR | P16473 | 5/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fenthion SCHEMBL1933208 | 0.85 | ALDH1A1 (0.81) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| Chlorpyrifos-Methyl SCHEMBL16446205 | 0.83 | TDP1 (0.62) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| Chlorpyrifos SCHEMBL1069405 | 0.83 | ALDH1A1 (0.89) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| SCHEMBL120468 | 0.80 | ALDH1A1 (0.70) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| Chlorpyrifos SCHEMBL21680 | 0.78 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| Chlorpyrifos SCHEMBL7908295 | 0.78 | ALDH1A1 (1.00) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| Chlorpyrifos SCHEMBL29011072 | 0.77 | ALDH1A1 (0.97) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| Chlorpyrifos SCHEMBL28566223 | 0.77 | ALDH1A1 (0.97) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| Chlorpyrifos SCHEMBL18228939 | 0.77 | ALDH1A1 (0.97) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 | |
| Chlorpyrifos SCHEMBL28945660 | 0.77 | ALDH1A1 (0.97) | ALDH1A1CYP3A4TSHRTDP1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5364627-A | Active particles dispersed throughout wall; drug delivery; sustained release when contacted with solvent | WM. WRIGLEY JR. COMPANY (US) | 1994-11-15 | — | — | US | disclosed |