Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.66 |
| ▸ | RAB9A | P51151 | 8/20 | 0.66 |
| ▸ | GRM5 | P41594 | 2/20 | 0.63 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.56 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.56 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.56 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.56 |
| ▸ | TLR4 | O00206 | 1/20 | 0.56 |
| ▸ | TLR2 | O60603 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16594642 | 0.83 | RAB9A (0.83) | NPC1RAB9ASORT1MEN1KMT2A | |
| SCHEMBL28697902 | 0.82 | NPC1 (0.77) | NPC1RAB9AGRM5SORT1MEN1 | |
| SCHEMBL997866 | 0.82 | RAB9A (0.89) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL29366822 | 0.82 | RAB9A (0.89) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL8556579 | 0.82 | GRM5 (0.67) | NPC1RAB9AGRM5SIRT2MEN1 | |
| SCHEMBL7348632 | 0.82 | RAB9A (0.66) | NPC1RAB9ASIRT2MEN1KMT2A | |
| SCHEMBL7096171 | 0.82 | RAB9A (0.66) | NPC1RAB9AGRM5SIRT2MEN1 | |
| SCHEMBL2943454 | 0.82 | RAB9A (0.66) | NPC1RAB9AGRM5SIRT2MEN1 | |
| SCHEMBL30643223 | 0.82 | GRM5 (0.67) | NPC1RAB9AGRM5SIRT2MEN1 | |
| SCHEMBL28671588 | 0.82 | GRM5 (0.67) | NPC1RAB9AGRM5SIRT2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109053558-B | Synthesis method of N-heterocyclic amide derivative | 贵州大学 | 2022-02-18 | — | — | CN | disclosed |
| EP-3426260-A1 | C-GLYCOSIDE COMPOUNDS USEFUL FOR TREATING DISEASE | Fimbrion Therapeutics, Inc. (US) | 2019-01-16 | — | — | EP | disclosed |
| WO-2017156508-A1 | C-GLYCOSIDE COMPOUNDS USEFUL FOR TREATING DISEASE | FIMBRION THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |
| WO-2017156508-A1 | C-GLYCOSIDE COMPOUNDS USEFUL FOR TREATING DISEASE | FIMBRION THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |