Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.66 |
| ▸ | NPC1 | O15118 | 3/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CNR2 | P34972 | 1/20 | 0.62 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.62 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28671588 | 1.00 | GRM5 (0.67) | GRM5POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL2194694 | 0.86 | GRM5 (0.65) | GRM5NPC1RAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL23406041 | 0.85 | ALDH1A1 (0.65) | GRM5NPC1RAB9AALDH1A1CNR2 | |
| SCHEMBL29743806 | 0.85 | ALDH1A1 (0.65) | GRM5NPC1RAB9AALDH1A1CNR2 | |
| SCHEMBL16996704 | 0.85 | RAB9A (0.66) | NPC1RAB9AALDH1A1SIRT2SMN1; SMN2 | |
| SCHEMBL10978860 | 0.84 | RAB9A (0.86) | NPC1RAB9AKCNMA1SMN1; SMN2MEN1 | |
| SCHEMBL29743832 | 0.83 | ADORA3 (0.61) | GRM5POLBALDH1A1CNR2CES1 | |
| SCHEMBL20712951 | 0.83 | ADORA3 (0.61) | GRM5POLBNPC1RAB9AALDH1A1 | |
| SCHEMBL23405883 | 0.83 | ADORA3 (0.61) | GRM5POLBALDH1A1CNR2CES1 | |
| SCHEMBL30926713 | 0.82 | ALDH1A1 (0.71) | POLBALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3653626-B1 | NOVEL 1H-PYRAZOLOPYRIDINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | DAEWOONG PHARMACEUTICAL CO LTD (KR) | 2025-09-17 | — | — | EP | claimed |
| EP-4006035-B1 | QUINAZOLINE DERIVATIVES AS TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF CANCER | NEUPHARMA INC (US) | 2023-11-22 | — | — | EP | claimed |