Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17914522 | 0.83 | L3MBTL1 (0.68) | L3MBTL1POLBNPC1PSIP1CA12 | |
| SCHEMBL17917627 | 0.80 | PSIP1 (0.46) | PSIP1ADRA2AKMT2A | |
| SCHEMBL13129161 | 0.80 | L3MBTL1 (0.64) | L3MBTL1POLBNPC1CA12CA1 | |
| SCHEMBL8170997 | 0.79 | L3MBTL1 (0.62) | L3MBTL1POLBNPC1PSIP1NLRP3 | |
| SCHEMBL8406220 | 0.79 | PSIP1 (0.49) | POLBPSIP1ADRA2ANPSR1KMT2A | |
| SCHEMBL8152754 | 0.77 | KMT2A (0.44) | POLBPSIP1CA2PTGES2ADRA2A | |
| SCHEMBL18921155 | 0.77 | PSIP1 (0.42) | PSIP1CA1CA2CA9PTGES2 | |
| SCHEMBL5607024 | 0.75 | L3MBTL1 (1.00) | L3MBTL1POLBNPC1CA12CA1 | |
| SCHEMBL21544195 | 0.74 | L3MBTL1 (0.70) | L3MBTL1POLBNPC1CA12CA1 | |
| SCHEMBL15614459 | 0.74 | L3MBTL1 (0.70) | L3MBTL1POLBNPC1CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758492-B2 | IDO inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-12 | — | — | US | disclosed |