Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ADH1B | P00325 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.32 |
| ▸ | ADH1A | P07327 | 1/20 | 0.32 |
| ▸ | ADH4 | P08319 | 1/20 | 0.32 |
| ▸ | ADH7 | P40394 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19413993 | 0.88 | OPRM1 (0.42) | OPRM1PLA2G1BPLA2G2ASPHK1LMNA | |
| SCHEMBL5949009 | 0.81 | PLA2G1B (0.39) | OPRM1PLA2G1BPLA2G2ACA1SPHK1 | |
| SCHEMBL19333378 | 0.80 | CYP1A2 (0.31) | CA1 | |
| SCHEMBL15013530 | 0.79 | PLA2G1B (0.38) | OPRM1PLA2G1BPLA2G2ALMNADNM1 | |
| SCHEMBL118906 | 0.79 | PLA2G1B (0.42) | OPRM1PLA2G1BPLA2G2ASPHK1LMNA | |
| SCHEMBL29286819 | 0.79 | PLA2G1B (0.42) | OPRM1PLA2G1BPLA2G2ASPHK1LMNA | |
| SCHEMBL21658546 | 0.78 | OPRM1 (0.34) | OPRM1PLA2G1BPLA2G2ALMNADNM1 | |
| SCHEMBL23682670 | 0.77 | OPRM1 (0.41) | OPRM1PLA2G1BPLA2G2ASPHK1LMNA | |
| SCHEMBL22336141 | 0.77 | — | — | |
| SCHEMBL115322 | 0.77 | PLA2G1B (0.41) | OPRM1PLA2G1BPLA2G2ASPHK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758492-B2 | IDO inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-12 | — | — | US | disclosed |