Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26421719 | 0.88 | CA12 (0.33) | CA12CA1CA2CA9 | |
| SCHEMBL22336141 | 0.85 | — | — | |
| SCHEMBL15015868 | 0.84 | CYP1A2 (0.36) | CYP1A2MAPK1CA12CA1CA2 | |
| SCHEMBL19333386 | 0.80 | OPRM1 (0.41) | CA1 | |
| SCHEMBL7672351 | 0.78 | — | — | |
| SCHEMBL21939363 | 0.78 | — | — | |
| SCHEMBL7672356 | 0.78 | — | — | |
| SCHEMBL2478250 | 0.75 | CYP1A2 (0.31) | CYP1A2MAPK1CA12CA1CA2 | |
| SCHEMBL9265208 | 0.75 | FDPS (0.34) | — | |
| SCHEMBL16549273 | 0.73 | PIK3CD (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758492-B2 | IDO inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-12 | — | — | US | disclosed |