Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | CTSG | P08311 | 2/20 | 0.49 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.49 |
| ▸ | CMA1 | P23946 | 2/20 | 0.49 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19575990 | 0.87 | NAAA (0.61) | NAAAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL4892494 | 0.81 | NAAA (0.49) | NAAAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL5271812 | 0.81 | NAAA (0.49) | NAAAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL27914837 | 0.81 | EPHX2 (0.48) | HDAC3HDAC1HDAC2L3MBTL1GAA | |
| Hippuric Acid SCHEMBL22559529 | 0.81 | NAAA (0.56) | NAAAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL27700892 | 0.78 | NAAA (0.65) | NAAAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL6684015 | 0.77 | CES2 (0.51) | NAAAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL6683969 | 0.77 | CES2 (0.51) | NAAAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL6686403 | 0.77 | CES2 (0.51) | NAAAPRSS1CTSGCTRB1CMA1 | |
| SCHEMBL1195165 | 0.77 | CES2 (0.51) | NAAAPRSS1CTSGCTRB1CMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758487-B2 | Hepatitis C virus inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2017-09-12 | — | — | US | disclosed |