Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.42 |
| ▸ | HTR2B | P41595 | 2/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25072598 | 0.82 | LMNA (0.40) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL14283780 | 0.81 | ALOX15 (0.40) | LMNACYP1A2HIF1ACYP3A4HPGD | |
| SCHEMBL67859 | 0.81 | LMNA (0.58) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL2790439 | 0.79 | LMNA (0.55) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL11144707 | 0.76 | LMNA (0.54) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL13773186 | 0.76 | LMNA (0.54) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL5157681 | 0.76 | LMNA (0.45) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL19334617 | 0.75 | LMNA (0.48) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL13588284 | 0.75 | LMNA (0.38) | LMNASLC6A2HTR2BTRPA1CHRM1 | |
| SCHEMBL71456 | 0.73 | LMNA (0.56) | LMNASLC6A2HTR2BTRPA1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9760030-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2017-09-12 | — | — | US | disclosed |