Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 5/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.37 |
| ▸ | XBP1 | P17861 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL383400 | 0.96 | ESR1 (0.60) | ESR1ESR2ALOX5MEN1KMT2A | |
| SCHEMBL29842572 | 0.96 | ESR1 (0.60) | ESR1ESR2ALOX5MEN1KMT2A | |
| SCHEMBL383087 | 0.93 | ESR1 (0.64) | ESR1ESR2MEN1KMT2ALMNA | |
| SCHEMBL29587240 | 0.93 | ESR1 (0.64) | ESR1ESR2MEN1KMT2ALMNA | |
| SCHEMBL19843860 | 0.90 | ESR1 (0.55) | ESR1ESR2ALOX5MEN1KMT2A | |
| SCHEMBL22580542 | 0.87 | ESR1 (0.57) | ESR1ESR2MEN1KMT2ALMNA | |
| SCHEMBL383048 | 0.87 | ESR1 (0.57) | ESR1ESR2ALOX5MEN1KMT2A | |
| SCHEMBL29842359 | 0.87 | ESR1 (0.57) | ESR1ESR2ALOX5MEN1KMT2A | |
| SCHEMBL13592688 | 0.86 | ESR1 (0.78) | ESR1ESR2MEN1KMT2ALMNA | |
| SCHEMBL5487840 | 0.86 | ESR1 (0.56) | ESR1ESR2ALOX5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9760030-B2 | Electrophotographic photosensitive member, process cartridge, and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2017-09-12 | — | — | US | disclosed |