SCHEMBL19334855

N=C(N)NCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CS)NC(=O)[C@@H](CCCNC(=N)N)N1C(=O)CNC1=O)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(N)=O

nearest known ligand 0.58

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	MC4R	P32245	10/20	0.58

▸	GHSR	Q92847	3/20	0.50

▸	IL23R	Q5VWK5	3/20	0.50

▸	NPY2R	P49146	2/20	0.49

▸	GRPR	P30550	1/20	0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL19334909	1.00	MC4R (0.58)	MC4RGHSRIL23RNPY2RGRPR
SCHEMBL20108505	1.00	MC4R (0.58)	MC4RGHSRIL23RNPY2RGRPR
SCHEMBL20108376	0.92	MC4R (0.57)	MC4RGHSRGRPR
SCHEMBL23430098	0.92	MC4R (0.59)	MC4RGHSR
SCHEMBL14511692	0.90	MC4R (0.71)	MC4RGHSRIL23RNPY2R
SCHEMBL20108313	0.88	IL23R (0.49)	MC4RIL23R
SCHEMBL23430256	0.88	IL23R (0.48)	MC4RIL23R
SCHEMBL20108406	0.87	MC4R (0.61)	MC4RGHSRIL23RNPY2RGRPR
SCHEMBL14511696	0.87	MC4R (0.67)	MC4RGHSRIL23RNPY2R
SCHEMBL20108277	0.85	MC4R (0.61)	MC4RGHSRIL23RGRPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-9758549-B2	Melanocortin receptor ligands modified with hydantoin	IPSEN PHARMA S.A.S. (FR)	2017-09-12	—	—	US	disclosed