SCHEMBL20108505

SCHEMBL20108505

N=C(N)NCCC[C@H](NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CS)NC(=O)[C@H](CCCNC(=N)N)N1C(=O)CNC1=O)C(=O)NC(Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(N)=O

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 10/20 0.58
▸ GHSR Q92847 3/20 0.50
▸ IL23R Q5VWK5 3/20 0.50
▸ NPY2R P49146 2/20 0.49
▸ GRPR P30550 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19334855 1.00 MC4R (0.58) MC4RGHSRIL23RNPY2RGRPR
SCHEMBL19334909 1.00 MC4R (0.58) MC4RGHSRIL23RNPY2RGRPR
SCHEMBL20108376 0.92 MC4R (0.57) MC4RGHSRGRPR
SCHEMBL23430098 0.92 MC4R (0.59) MC4RGHSR
SCHEMBL14511692 0.90 MC4R (0.71) MC4RGHSRIL23RNPY2R
SCHEMBL20108313 0.88 IL23R (0.49) MC4RIL23R
SCHEMBL23430256 0.88 IL23R (0.48) MC4RIL23R
SCHEMBL20108406 0.87 MC4R (0.61) MC4RGHSRIL23RNPY2RGRPR
SCHEMBL14511696 0.87 MC4R (0.67) MC4RGHSRIL23RNPY2R
SCHEMBL20108277 0.85 MC4R (0.61) MC4RGHSRIL23RGRPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180118784-A1 MELANOCORTIN RECEPTOR LIGANDS MODIFIED WITH HYDANTOIN IPSEN PHARMA S.A.S. (FR) 2018-05-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180118784-A1 MELANOCORTIN RECEPTOR LIGANDS MODIFIED WITH HYDANTOIN MC4R, MC3R, MC1R MC4R 1/4885GHSR 103/4885IL23R 420/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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