SCHEMBL14511696

SCHEMBL14511696

CC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CS)C(N)=O

nearest known ligand 0.67

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 6/20 0.67
▸ IL23R Q5VWK5 10/20 0.62
▸ GHSR Q92847 4/20 0.61
▸ NPY2R P49146 3/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14511692 0.97 MC4R (0.71) MC4RIL23RGHSRNPY2R
SCHEMBL23152931 0.91 MC4R (0.71) MC4RIL23RGHSR
SCHEMBL28940915 0.91 MC4R (0.71) MC4RIL23RGHSR
SCHEMBL23483109 0.91 MC4R (0.71) MC4RIL23RGHSR
SCHEMBL23484389 0.90 MC4R (0.69) MC4RIL23RGHSR
SCHEMBL19334909 0.87 MC4R (0.58) MC4RIL23RGHSRNPY2R
SCHEMBL19334855 0.87 MC4R (0.58) MC4RIL23RGHSRNPY2R
SCHEMBL20108505 0.87 MC4R (0.58) MC4RIL23RGHSRNPY2R
SCHEMBL31406959 0.84 IL23R (0.62) MC4RIL23R
SCHEMBL23430227 0.84 MC4R (0.57) MC4RIL23RGHSRNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070105759-A1 Melanocortin receptor 4 (mc4) agonists and their uses ELI LILLY AND COMPANY (US) 2007-05-10 — — US disclosed
US-20070105759-A1 Melanocortin receptor 4 (mc4) agonists and their uses ELI LILLY AND COMPANY (US) 2007-05-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070105759-A1 Melanocortin receptor 4 (mc4) agonists and their uses MC4R, MC3R, MC1R MC4R 1/4885IL23R 809/4885GHSR 34/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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