Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 6/20 | 0.46 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 12/20 | 0.42 |
| ▸ | CLK3 | P49761 | 11/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 11/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17555701 | 0.74 | MAP4K4 (0.48) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17555612 | 0.69 | MAP4K4 (0.41) | WNT1CLK2CLK3DYRK1AMAP4K4 | |
| SCHEMBL17629075 | 0.69 | MAP4K4 (0.43) | WNT1CLK2CLK3DYRK1AMAP4K4 | |
| SCHEMBL17568762 | 0.68 | MAP4K4 (0.48) | WNT1CLK2CLK3DYRK1AMAP4K4 | |
| SCHEMBL20966019 | 0.67 | WNT1 (0.63) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17588944 | 0.65 | MAP4K4 (0.48) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17567118 | 0.65 | CLK2 (0.44) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL15301579 | 0.64 | CLK2 (0.44) | WNT1TGFBR1CLK2CLK3DYRK1A | |
| SCHEMBL17562434 | 0.63 | NOS2 (0.43) | CLK2CLK3DYRK1AMAP4K4 | |
| SCHEMBL17555868 | 0.62 | MAP4K4 (0.43) | WNT1CLK2CLK3DYRK1AMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9758531-B2 | 3-(3H-imidazo[4,5-B]pyridin-2-yl)-1H-pyrazolo[3,4-B]pyridine and therapeutic uses thereof | SAMUMED, LLC (US) | 2017-09-12 | — | — | US | disclosed |