Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.48 |
| ▸ | GPBAR1 | Q8TDU6 | 4/20 | 0.47 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1419915 | 0.81 | ALOX5 (0.72) | ALOX5FFAR1AKR1B1CYSLTR1GPBAR1 | |
| SCHEMBL7459197 | 0.80 | CYSLTR1 (0.54) | ALOX5CYSLTR1GPBAR1CYSLTR2 | |
| SCHEMBL1558372 | 0.78 | CYSLTR1 (0.54) | ALOX5FFAR1AKR1B1CYSLTR1GPBAR1 | |
| SCHEMBL1558239 | 0.78 | FFAR1 (0.55) | ALOX5FFAR1AKR1B1CYSLTR1GPBAR1 | |
| SCHEMBL9431239 | 0.78 | ALOX5 (0.50) | ALOX5FFAR1AKR1B1CYSLTR1CYSLTR2 | |
| SCHEMBL9033146 | 0.77 | FFAR1 (0.54) | ALOX5FFAR1AKR1B1CYSLTR1GPBAR1 | |
| SCHEMBL9032897 | 0.77 | FFAR1 (0.54) | ALOX5FFAR1AKR1B1CYSLTR1GPBAR1 | |
| SCHEMBL9431922 | 0.76 | MEN1 (0.53) | ALOX5CYSLTR1CYSLTR2 | |
| SCHEMBL9034329 | 0.76 | FFAR1 (0.53) | ALOX5FFAR1AKR1B1CYSLTR1GPBAR1 | |
| SCHEMBL9034967 | 0.76 | FFAR1 (0.55) | ALOX5FFAR1AKR1B1CYSLTR1GPBAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2297133-B1 | 1, 2 DISUBSTITUTED HETEROCYCLIC COMPOUNDS | FORUM PHARMACEUTICALS INC (US) | 2017-09-13 | — | — | EP | disclosed |