Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2RL1 | P55085 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 7/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18024071 | 0.79 | KDM4E (0.36) | — | |
| SCHEMBL20081417 | 0.79 | NFE2L2 (0.34) | NFE2L2 | |
| SCHEMBL20274081 | 0.78 | ERN1 (0.32) | — | |
| SCHEMBL23656272 | 0.78 | ALDH1A1 (0.30) | — | |
| SCHEMBL20274086 | 0.78 | ERN1 (0.32) | — | |
| SCHEMBL20274085 | 0.77 | HRH4 (0.38) | NFE2L2HRH4 | |
| SCHEMBL22917369 | 0.76 | ALDH1A1 (0.34) | — | |
| SCHEMBL23761786 | 0.76 | KDM4E (0.37) | — | |
| SCHEMBL9928484 | 0.75 | MAPT (0.40) | — | |
| SCHEMBL25481760 | 0.75 | TYR (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3428162-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | BOEHRINGER INGELHEIM ANIMAL HEALTH USA INC (US) | 2021-05-05 | — | — | EP | disclosed |
| EP-3428162-A1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | Merial Inc. (US) | 2019-01-16 | — | — | EP | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |
| EP-2297133-B1 | 1, 2 DISUBSTITUTED HETEROCYCLIC COMPOUNDS | FORUM PHARMACEUTICALS INC (US) | 2017-09-13 | — | — | EP | disclosed |