Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 8/20 | 0.40 |
| ▸ | CTSS | P25774 | 4/20 | 0.40 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5691699 | 0.88 | CA1 (0.46) | CTSKCTSSPLA2G2CCA1CA2 | |
| SCHEMBL28467147 | 0.85 | CA1 (0.40) | CTSKCTSSPLA2G2CCA1CA2 | |
| SCHEMBL28467148 | 0.85 | CA1 (0.40) | CTSKCTSSPLA2G2CCA1CA2 | |
| SCHEMBL15376153 | 0.83 | CTSK (0.47) | CTSKCTSSPLA2G2CCA1CA2 | |
| SCHEMBL20276859 | 0.83 | CTSK (0.47) | CTSKCTSSPLA2G2CCA1CA2 | |
| SCHEMBL19337817 | 0.83 | CTSK (0.47) | CTSKCTSSPLA2G2CCA1CA2 | |
| SCHEMBL20178106 | 0.82 | CA1 (0.40) | CTSKCTSSCA1CA2CA7 | |
| SCHEMBL25319084 | 0.82 | CA1 (0.41) | CTSKCTSSPLA2G2CCA1CA2 | |
| SCHEMBL25319090 | 0.82 | CA1 (0.41) | CTSKCTSSPLA2G2CCA1CA2 | |
| SCHEMBL25320182 | 0.82 | APLNR (0.44) | CTSKCTSSPLA2G2CCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2834234-B1 | FUSED CYCLOPENTYL ANTAGONISTS OF CCR2 | JANSSEN PHARMACEUTICA NV (BE) | 2017-09-13 | — | — | EP | disclosed |