Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | APLNR | P35414 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11261569 | 0.83 | POLB (0.42) | KMT2AL3MBTL1MAPTALDH1A1MEN1 | |
| SCHEMBL11268894 | 0.81 | MTNR1A (0.46) | HPGDKMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL11260727 | 0.81 | MTNR1A (0.43) | HPGDKMT2AL3MBTL1MAPTALDH1A1 | |
| Stepronin SCHEMBL19338 | 0.80 | ELANE (0.56) | ELANEHPGDKMT2AMAPTALDH1A1 | |
| Stepronin SCHEMBL19339 | 0.80 | ELANE (0.56) | ELANEHPGDKMT2AMAPTALDH1A1 | |
| Stepronin SCHEMBL1651441 | 0.78 | ELANE (0.54) | ELANEHPGDKMT2AMAPTGAA | |
| SCHEMBL11268041 | 0.74 | KIF11 (0.41) | HPGDKMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL11179639 | 0.73 | MTNR1A (0.47) | HPGDKMT2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL11132160 | 0.69 | TSHR (0.42) | ELANEHPGDKMT2AAPLNRCTNNB1 | |
| SCHEMBL10589127 | 0.69 | ELANE (0.53) | ELANEHPGDKMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405638-A | ANTITUSSIVE AGENTS; ANTIINFLAMMATORY AGENTS; RESPIRATORY SYSTEM DISORDERS | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A (IT) | 1983-09-20 | — | — | US | disclosed |