Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.53 |
| ▸ | NT5E | P21589 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 8/20 | 0.47 |
| ▸ | ACP1 | P24666 | 2/20 | 0.47 |
| ▸ | PTPRF | P10586 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.40 |
| ▸ | IL1B | P01584 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 4/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.38 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.38 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13759951 | 0.85 | LMNA (0.52) | LMNASMN1; SMN2GPBAR1NT5EPTPN1 | |
| SCHEMBL13759952 | 0.85 | LMNA (0.52) | LMNASMN1; SMN2GPBAR1NT5EPTPN1 | |
| SCHEMBL19338168 | 0.83 | LMNA (0.50) | LMNASMN1; SMN2GPBAR1NT5EPTPN1 | |
| SCHEMBL19338166 | 0.83 | GPBAR1 (0.66) | LMNASMN1; SMN2GPBAR1NT5EPTPN1 | |
| SCHEMBL14344859 | 0.83 | GPBAR1 (0.66) | LMNASMN1; SMN2GPBAR1NT5EPTPN1 | |
| SCHEMBL19338147 | 0.81 | LMNA (0.48) | LMNASMN1; SMN2GPBAR1NT5EPTPN1 | |
| SCHEMBL14345996 | 0.81 | LMNA (0.48) | LMNASMN1; SMN2GPBAR1NT5EPTPN1 | |
| SCHEMBL19338149 | 0.81 | GPBAR1 (0.48) | LMNASMN1; SMN2GPBAR1NT5EPTPN1 | |
| SCHEMBL14345254 | 0.81 | LMNA (0.48) | LMNASMN1; SMN2GPBAR1NT5EPTPN1 | |
| SCHEMBL10074445 | 0.80 | GPBAR1 (0.57) | LMNASMN1; SMN2GPBAR1NT5EPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190209582-A1 | COMPOSITIONS COMPRISING TRITERPENOIDS | REGENERA PHARMA LTD. (IL) | 2019-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190209582-A1 | COMPOSITIONS COMPRISING TRITERPENOIDS | PARK7, SNCA, APP | LMNA 3158/4885SMN1; SMN2 1342/4885GPBAR1 313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.