Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 10/20 | 0.40 |
| ▸ | F11 | P03951 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.32 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.32 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL748939 | 0.82 | MAPK13 (0.39) | PRCPF11F2MAPK13MAPK12 | |
| SCHEMBL204507 | 0.81 | CYP2C9 (0.43) | PRCPF11F2HDAC1CYP3A4 | |
| SCHEMBL9980233 | 0.81 | CYP2C9 (0.43) | PRCPF11F2HDAC1CYP3A4 | |
| SCHEMBL2756981 | 0.78 | HPGDS (0.42) | PRCPMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL2707959 | 0.78 | HPGDS (0.42) | PRCPMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL204280 | 0.78 | HPGDS (0.42) | PRCPMAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL751395 | 0.77 | CYP2C9 (0.41) | PRCPF11F2HDAC1CYP3A4 | |
| SCHEMBL12098861 | 0.75 | CYP2C9 (0.50) | PRCPHDAC1CYP3A4CYP2C9NR1I2 | |
| SCHEMBL2707990 | 0.73 | CYP3A4 (0.61) | F11F2CYP3A4CYP2C9NR1I2 | |
| SCHEMBL205945 | 0.73 | CYP3A4 (0.61) | F11F2CYP3A4CYP2C9NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3002281-B1 | ANTIVIRAL COMPOUNDS | GILEAD PHARMASSET LLC (US) | 2017-09-13 | — | — | EP | disclosed |