Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | PRCP | P42785 | 8/20 | 0.38 |
| ▸ | PTGES | O14684 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | F11 | P03951 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12492101 | 0.90 | PRCP (0.38) | MAPK13MAPK12MAPK11MAPK14PRCP | |
| SCHEMBL204280 | 0.85 | HPGDS (0.42) | MAPK13MAPK12MAPK11MAPK14PRCP | |
| SCHEMBL2707959 | 0.85 | HPGDS (0.42) | MAPK13MAPK12MAPK11MAPK14PRCP | |
| SCHEMBL2756981 | 0.85 | HPGDS (0.42) | MAPK13MAPK12MAPK11MAPK14PRCP | |
| SCHEMBL2590140 | 0.84 | PRCP (0.43) | MAPK13MAPK12MAPK11MAPK14PRCP | |
| SCHEMBL1314945 | 0.84 | CYP2C9 (0.43) | MAPK13MAPK12MAPK11MAPK14PRCP | |
| SCHEMBL12098861 | 0.84 | CYP2C9 (0.50) | PRCPNR1I2ABCB11CYP3A4CYP2C9 | |
| SCHEMBL19339809 | 0.82 | PRCP (0.40) | MAPK13MAPK12MAPK11MAPK14PRCP | |
| SCHEMBL2756969 | 0.80 | CYP3A4 (0.61) | NR1I2ABCB11CYP3A4CYP2C9OPRK1 | |
| SCHEMBL205945 | 0.80 | CYP3A4 (0.61) | NR1I2ABCB11CYP3A4CYP2C9OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2430014-A1 | ANTIVIRAL COMPOUNDS | Gilead Sciences, Inc. (US) | 2012-03-21 | — | — | EP | disclosed |
| WO-2010132601-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2010-11-18 | — | — | WO | disclosed |