SCHEMBL19340288

SCHEMBL19340288

C[Si]1(C)c2ccccc2N(c2cc(C#N)c(-c3c(C#N)cc(N4c5ccccc5[Si](C)(C)c5ccccc54)cc3C#N)c(C#N)c2)c2ccccc21

nearest known ligand 0.35

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.35
KDM4E B2RXH2 2/20 0.35
GLA P06280 1/20 0.35
GAA P10253 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
LMNA P02545 1/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
IMPDH2 P12268 1/20 0.33
TSHR P16473 1/20 0.32
HIF1A Q16665 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
HTR2A P28223 1/20 0.30
HTR6 P50406 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19345010 0.85 ALDH1A1 (0.35) ALDH1A1KDM4EGLAGAASMN1; SMN2
SCHEMBL19340289 0.85 ALDH1A1 (0.33) ALDH1A1KDM4ESMN1; SMN2LMNAHPGD
SCHEMBL19345084 0.83 TSHR (0.36) TSHRMAOAMAOB
SCHEMBL19344972 0.82 ALDH1A1 (0.35) ALDH1A1KDM4EGLAGAASMN1; SMN2
SCHEMBL19340268 0.79 TSHR (0.33) ALDH1A1KDM4EGLAGAATSHR
SCHEMBL19344945 0.78 TSHR (0.42) ALDH1A1TSHRMAOAMAOB
SCHEMBL19345046 0.76 IMPDH2 (0.34) ALDH1A1KDM4EGLAGAALMNA
SCHEMBL19344981 0.76 KDM4E (0.36) ALDH1A1KDM4EGLAGAAIMPDH2
SCHEMBL19368321 0.75 ALDH1A1 (0.39) ALDH1A1GAAHPGDMAOA
SCHEMBL30253548 0.75 ALDH1A1 (0.39) ALDH1A1GAAHPGDMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170263871-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2017-09-14 US disclosed
US-20170263871-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2017-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170263871-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE OR10J3, RPS10, OR51E2 ALDH1A1 616/4885KDM4E 3155/4885GLA 2917/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.