Cis-Urocanic Acid

Cis-Urocanic Acid

SCHEMBL1136889

O=C(O)C=Cc1cnc[nH]1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 1.00
TSHR P16473 2/20 1.00
KDM4E B2RXH2 2/20 1.00
BLM P54132 1/20 1.00
NPSR1 Q6W5P4 1/20 1.00
MEN1 O00255 1/20 0.64
KMT2A Q03164 1/20 0.64
AOC1 P19801 2/20 0.48
PADI4 Q9UM07 1/20 0.45
SMYD3 Q9H7B4 1/20 0.45
ALDH1A1 P00352 2/20 0.41
GABRA1 P14867 1/20 0.41
NFKB1 P19838 1/20 0.41
GABRR1 P24046 1/20 0.41
GABRR2 P28476 1/20 0.41
GABRA5 P31644 1/20 0.41
GABRB2 P47870 1/20 0.41
GABRA4 P48169 1/20 0.41
MAPT P10636 1/20 0.40
PMP22 Q01453 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cis-Urocanic Acid SCHEMBL338885 1.00 CYP3A4 (1.00) CYP3A4TSHRKDM4EBLMNPSR1
Cis-Urocanic Acid SCHEMBL12963908 1.00 CYP3A4 (1.00) CYP3A4TSHRKDM4EBLMNPSR1
SCHEMBL15668642 0.82 CYP3A4 (0.70) CYP3A4TSHRKDM4EBLMNPSR1
SCHEMBL23749602 0.82 CYP3A4 (0.70) CYP3A4TSHRKDM4EBLMNPSR1
SCHEMBL8086657 0.79
SCHEMBL8552929 0.78 KMT2A (1.00) CYP3A4TSHRKDM4EBLMNPSR1
SCHEMBL21334959 0.78 KMT2A (1.00) CYP3A4TSHRKDM4EBLMNPSR1
SCHEMBL25101013 0.78 KDM4E (0.64) CYP3A4TSHRKDM4EBLMNPSR1
SCHEMBL2567149 0.74 MEN1 (0.69) CYP3A4TSHRKDM4EBLMNPSR1
SCHEMBL11598554 0.74 MEN1 (0.69) CYP3A4TSHRKDM4EBLMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1060223-B1 PHOTOCHROMIC COATING COMPOUND AND SUBSTRATE COATED WITH SAME INST NEUE MAT GEMEIN GMBH (DE) 2004-08-18 EP claimed
US-6639039-B1 Polysiloxane precondensate having curable glycidol or methacryl functionality, dye, stabilizer and particles; light and scratch resistance Institut für Neue Materialien Gemeinnützige GmbH (DE) 2003-10-28 US claimed
EP-1060223-A1 PHOTOCHROMIC COATING COMPOUND AND SUBSTRATE COATED WITH SAME Institut Für Neue Materialien gem. GmbH (DE) 2000-12-20 EP claimed
WO-1999041326-A1 PHOTOCHROMIC COATING COMPOUND AND SUBSTRATE COATED WITH SAME INSTITUT FÜR NEUE MATERIALIEN GEM. GMBH (DE) 1999-08-19 WO claimed
US-20250205140-A1 SURFACTANT AND COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-06-26 US disclosed
EP-4512872-A1 SURFACTANT AND COSMETIC SHIN-ETSU CHEMICAL CO., LTD. (JP) 2025-02-26 EP disclosed
US-20240409517-A1 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2024-12-12 US disclosed
EP-4415561-A2 ORGANIC COMPOUNDS Givaudan SA (CH) 2024-08-21 EP disclosed
US-20230346831-A1 METHODS FOR TREATING METASTATIC CANCER USING LOW DOSE CARBON MONOXIDE CORNELL UNIVERSITY (US) 2023-11-02 US disclosed
WO-2023062110-A2 ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2023-04-20 WO disclosed
US-20220244263-A1 METHODS FOR TREATING SMALL CELL NEUROENDOCRINE AND RELATED CANCERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2022-08-04 US disclosed
US-20110190351-A1 Benzoimidazole Derivatives and Glycogen Synthase Kinase-3 Beta Inhibitors Containing the Same ONCOTHERAPY SCIENCE, INC. (JP) 2011-08-04 US disclosed
EP-1883534-B1 REGENERATABLE, STRUCTURED PLATE COMPRISING OXIDATION CATALYSTS LEIBNIZ INST NEUE MATERIALIEN (DE) 2010-12-01 EP disclosed
WO-2010014794-A1 BENZOIMIDAZOLE DERIVATIVES AND GLYCOGEN SYNTHASE KINASE-3 BETA INHIBITORS CONTAINING THE SAME ONCOTHERAPY SCIENCE, INC. (JP) 2010-02-04 WO disclosed
US-20090035703-A1 Regeneratable, structured plate comprising oxidation catalysts LEIBNIZ-INSTITUT FUER NEUE MATERIALIEN GEMEINNUETZIGE GMBH (DE) 2009-02-05 US disclosed
EP-1883534-A1 REGENERATABLE, STRUCTURED PLATE COMPRISING OXIDATION CATALYSTS Leibniz-Institut für Neue Materialien gemeinnützige GmbH (DE) 2008-02-06 EP disclosed
WO-2006125635-A1 REGENERATABLE, STRUCTURED PLATE COMPRISING OXIDATION CATALYSTS LEIBNIZ-INSTITUT FÜR NEUE MATERIALIEN GEMEINNÜTZIGE GMBH (DE) 2006-11-30 WO disclosed
EP-1060223-B1 PHOTOCHROMIC COATING COMPOUND AND SUBSTRATE COATED WITH SAME INST NEUE MAT GEMEIN GMBH (DE) 2004-08-18 EP disclosed
EP-1060223-A1 PHOTOCHROMIC COATING COMPOUND AND SUBSTRATE COATED WITH SAME Institut Für Neue Materialien gem. GmbH (DE) 2000-12-20 EP disclosed
WO-1999041326-A1 PHOTOCHROMIC COATING COMPOUND AND SUBSTRATE COATED WITH SAME INSTITUT FÜR NEUE MATERIALIEN GEM. GMBH (DE) 1999-08-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240409517-A1 ORGANIC COMPOUNDS HTR3C, HTR3A, H1-0 CYP3A4 1043/4885TSHR 2055/4885KDM4E 272/4885
US-20110190351-A1 Benzoimidazole Derivatives and Glycogen Synthase Kinase-3 Beta Inhibitors Containing the Same GSK3B, GSK3A, GYS2 CYP3A4 1466/4885TSHR 4605/4885KDM4E 1394/4885
US-20250205140-A1 SURFACTANT AND COSMETIC SGMS1, H1-0, SGMS2 CYP3A4 3843/4885TSHR 1227/4885KDM4E 3645/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.