Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPT1A | P50416 | 3/20 | 0.46 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.40 |
| ▸ | TRPC7 | Q9HCX4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.37 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12556703 | 1.00 | CPT1A (0.46) | CPT1ATRPC3TRPC7LMNAENPP2 | |
| SCHEMBL12556487 | 0.87 | JAK1 (0.41) | TRPC3TRPC7ENPP2HTR2C | |
| SCHEMBL12556500 | 0.86 | ALDH1A1 (0.42) | CPT1ALMNAENPP2HTR2CTLR7 | |
| SCHEMBL1934194 | 0.86 | ALDH1A1 (0.42) | CPT1ALMNAENPP2HTR2CTLR7 | |
| SCHEMBL12556304 | 0.81 | ENPP2 (0.43) | CPT1AENPP2HTR2CCPT2AGTR2 | |
| SCHEMBL12556301 | 0.78 | CPT1A (0.41) | CPT1ATRPC3TRPC7ENPP2 | |
| SCHEMBL9611499 | 0.76 | KLK7 (0.42) | HTR2CAGTR2 | |
| SCHEMBL12556713 | 0.75 | CPT1A (0.40) | CPT1AENPP2 | |
| SCHEMBL12556330 | 0.75 | GBA1 (0.40) | TRPC3TRPC7 | |
| SCHEMBL9611472 | 0.75 | HTR2C (0.41) | LMNAHTR2CAGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011068926-A1 | IAP INHIBITORS | TETRALOGIC PHARMACEUTICALS CORP. (US) | 2011-06-09 | — | — | WO | disclosed |