Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.39 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | IL1R1 | P14778 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10205988 | 1.00 | KDM4E (0.55) | KDM4EL3MBTL1ATMMAPK8MAPK9 | |
| SCHEMBL10206021 | 0.98 | KDM4E (0.57) | KDM4EL3MBTL1ATMMAPK8MAPK9 | |
| SCHEMBL13562925 | 0.98 | L3MBTL1 (0.52) | KDM4EL3MBTL1ATMMAPK8MAPK9 | |
| SCHEMBL15073662 | 0.97 | KDM4E (0.55) | KDM4EL3MBTL1ATMMAPK8MAPK9 | |
| SCHEMBL31670 | 0.94 | L3MBTL1 (0.49) | KDM4EL3MBTL1ATMMAPK8MAPK9 | |
| SCHEMBL13562911 | 0.93 | KDM4E (0.53) | KDM4EL3MBTL1ATMMAPK8MAPK9 | |
| SCHEMBL15144211 | 0.91 | KDM4E (0.55) | KDM4EL3MBTL1ATMMAPK8MAPK9 | |
| SCHEMBL31707 | 0.91 | KDM4E (0.50) | KDM4EL3MBTL1ATMMAPK8MAPK9 | |
| SCHEMBL15073718 | 0.90 | KDM4E (0.47) | KDM4EL3MBTL1ATMMAPK8MAPK9 | |
| SCHEMBL17589462 | 0.90 | KDM4E (0.47) | KDM4EL3MBTL1ATMMAPK8MAPK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170263869-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) | 2017-09-14 | — | — | US | disclosed |
| US-20170263869-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) | 2017-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170263869-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT | VDAC1, VDAC3, ELOC | KDM4E 1130/4885L3MBTL1 340/4885ATM 3114/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.