Sugi Predict

Sugi Predict / Compounds / SCHEMBL193427

SCHEMBL193427

SCHEMBL193427

CCCCc1cccc(C=O)c1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 1/20 0.49
▸ PTGS2 P35354 1/20 0.49
▸ ERN1 O75460 4/20 0.48
▸ IAPP P10997 4/20 0.46
▸ TLR2 O60603 1/20 0.46
▸ TLR1 Q15399 1/20 0.46
▸ TLR6 Q9Y2C9 1/20 0.46
▸ ELANE P08246 1/20 0.44
▸ CTSG P08311 1/20 0.44
▸ GABRA1 P14867 1/20 0.44
▸ GABRB2 P47870 1/20 0.44
▸ BID P55957 3/20 0.43
▸ MCL1 Q07820 3/20 0.43
▸ BCL2L1 Q07817 2/20 0.43
▸ BAK1 Q16611 2/20 0.43
▸ KAT8 Q9H7Z6 2/20 0.43
▸ PPARG P37231 1/20 0.43
▸ PPARA Q07869 1/20 0.43
▸ EP300 Q09472 1/20 0.43
▸ KAT2A Q92830 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7091232 0.97 ALOX5 (0.46) ALOX5PTGS2ERN1IAPPTLR2
SCHEMBL1527091 0.95 ALOX5 (0.55) ALOX5PTGS2ERN1IAPPTLR2
SCHEMBL11503688 0.93 ALOX5 (0.54) ALOX5PTGS2ERN1ELANECTSG
SCHEMBL8530625 0.93 ALOX5 (0.54) ALOX5PTGS2ERN1ELANECTSG
SCHEMBL8527689 0.93 ALOX5 (0.54) ALOX5PTGS2ERN1ELANECTSG
SCHEMBL6910210 0.93 ALOX5 (0.54) ALOX5PTGS2ERN1ELANECTSG
SCHEMBL8531468 0.93 ALOX5 (0.54) ALOX5PTGS2ERN1ELANECTSG
SCHEMBL1527072 0.93 ALOX5 (0.54) ALOX5PTGS2ERN1ELANECTSG
SCHEMBL4619860 0.92 ALOX5 (0.53) ALOX5PTGS2ERN1ELANECTSG
SCHEMBL29953931 0.89 ERN1 (0.52) ALOX5PTGS2ERN1IAPPTLR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118185107-A TPU film with optical texture effect and application of TPU film in injection molding part 广东中鼎科技发展有限公司 2024-06-14 — — CN claimed
CN-118050345-A Metal organic cage-based two-chiral probe, preparation method thereof and kit 郑州大学 2024-05-17 — — CN claimed
CN-115128051-B Fluorescence detection method for detecting 3-nitropropionic acid in sugarcane and sugarcane products 广西壮族自治区农业科学院 2024-04-26 — — CN claimed
CN-115096862-B Ratio type fluorescence detection method for rapidly detecting trace water in organic solvent 广西壮族自治区农业科学院 2024-04-26 — — CN claimed
CN-102382256-A Catalyst system and preparation method for norbornene and isoprene copolymer UNIV ZHEJIANG 2012-03-21 — — CN claimed
CN-101270112-A Preparation of polymerization type chiral catalyst, preparation and application of cyclic carbonates with optical activity UNIV LANZHOU (CN) 2008-09-24 — — CN claimed
CN-1228356-C Norbornene polymerization catalyst system and its preparing process CHINESE ACAD INST CHEMISTRY (CN) 2005-11-23 — — CN claimed
CN-1200017-C Nickel compound catalyst system for polymerization of norbornene and its prepn CHINESE ACAD INST CHEMISTRY (CN) 2005-05-04 — — CN claimed
CN-1589136-A Pharmaceutical and cosmetic compositions containing aromatic aldehydes bearing oxygen-containing groups CUTANIX CORP (US) 2005-03-02 — — CN claimed
CN-1167720-C Polymeric catalyst system of norbornaene and its preparing process 中国科学院化学研究所 2004-09-22 — — CN claimed
CN-1139606-C Norbornene catalytic system and its preparation method and application 中国科学院化学研究所 2004-02-25 — — CN claimed
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments CUTANIX CORPORATION 2003-08-21 — — US claimed
CN-1394685-A Norbornene catalytic system and its preparation method and application CHINESE ACAD INST CHEMISTRY (CN) 2003-02-05 — — CN claimed
CN-1390867-A Polymeric catalyst system of norbornaene and its preparing process CHINESE ACAD INST CHEMISTRY (CN) 2003-01-15 — — CN claimed
CN-1388139-A Norbornene polymerization catalyst system and its preparing process CHINESE ACAD INST CHEMISTRY (CN) 2003-01-01 — — CN claimed
CN-1388140-A Nickel compound catalyst system for polymerization of norbornene and its prepn CHINESE ACAD INST CHEMISTRY (CN) 2003-01-01 — — CN claimed
CN-118185107-A TPU film with optical texture effect and application of TPU film in injection molding part 广东中鼎科技发展有限公司 2024-06-14 — — CN disclosed
CN-118050345-A Metal organic cage-based two-chiral probe, preparation method thereof and kit 郑州大学 2024-05-17 — — CN disclosed
US-4133729-A Production of 1,2-bis(hydroxy-phenyl)ethane-1,2-diols by electrolytic reduction MONSANTO COMPANY (US) 1979-01-09 — — US disclosed
US-4087336-A Electrolytic reductive coupling of hydroxybenzaldehydes MONSANTO COMPANY (US) 1978-05-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030157154-A1 Compositions containing hydroxy aromatic aldehydes and their use in treatments TYR, HRH1, HRH2 ALOX5 44/4885PTGS2 484/4885ERN1 4830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.