Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.52 |
| ▸ | TLR2 | O60603 | 1/20 | 0.49 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.49 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.47 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | IAPP | P10997 | 5/20 | 0.44 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | CTSG | P08311 | 1/20 | 0.42 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.41 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1527632 | 1.00 | ERN1 (0.52) | ERN1TLR2TLR1TLR6GABRA1 | |
| SCHEMBL7091232 | 0.93 | ALOX5 (0.46) | ERN1TLR2TLR1TLR6GABRA1 | |
| SCHEMBL193427 | 0.89 | ALOX5 (0.49) | ERN1TLR2TLR1TLR6GABRA1 | |
| SCHEMBL21002293 | 0.88 | ERN1 (0.59) | ERN1TLR2TLR1TLR6GABRA1 | |
| SCHEMBL1527091 | 0.88 | ALOX5 (0.55) | ERN1TLR2TLR1TLR6IAPP | |
| SCHEMBL29607733 | 0.86 | GABRA1 (0.64) | ERN1TLR2TLR1TLR6GABRA1 | |
| SCHEMBL1527079 | 0.86 | GABRA1 (0.64) | ERN1TLR2TLR1TLR6GABRA1 | |
| SCHEMBL11503688 | 0.86 | ALOX5 (0.54) | ERN1ELANECTSGALOX5PTGS2 | |
| SCHEMBL8531468 | 0.86 | ALOX5 (0.54) | ERN1ELANECTSGALOX5PTGS2 | |
| SCHEMBL6910210 | 0.86 | ALOX5 (0.54) | ERN1ELANECTSGALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |