SCHEMBL19343003

SCHEMBL19343003

CC(C)c1ccc2c(c1)N(c1ccc3ccccc3c1)/C(=C1\N(c3ccc4ccccc4c3)c3ccc(C(C)C)cc3N1c1ccc3ccccc3c1)N2c1ccc2ccccc2c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 1/20 0.44
UGT2B7 P16662 1/20 0.42
HTR3A P46098 2/20 0.38
KMT2A Q03164 3/20 0.37
POLB P06746 1/20 0.37
HTR2A P28223 1/20 0.36
HTR2C P28335 1/20 0.36
HTR2B P41595 1/20 0.36
HTR3E A5X5Y0 1/20 0.35
HTR3B O95264 1/20 0.35
HTR5A P47898 1/20 0.35
HTR3D Q70Z44 1/20 0.35
HTR3C Q8WXA8 1/20 0.35
SIGMAR1 Q99720 1/20 0.35
CYP1A2 P05177 3/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
MEN1 O00255 2/20 0.35
CYP2D6 P10635 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18905729 0.83 MGLL (0.48) KMT2APOLBMEN1HIF1ARAB9A
SCHEMBL17794507 0.81 HSP90AA1 (0.57) HSP90AA1HTR3AKMT2APOLBHTR3E
SCHEMBL19343002 0.81 CYP2A6 (0.52) HSP90AA1HTR3AKMT2APOLBHTR3E
SCHEMBL18905711 0.79 LMNA (0.42) KMT2ACYP2C19MEN1TSHRCYP3A4
SCHEMBL17794464 0.78 HSP90AA1 (0.50) HSP90AA1HTR3AKMT2APOLBHTR3E
SCHEMBL19343007 0.78 CYP1A2 (0.52) HSP90AA1HTR3AKMT2APOLBHTR3E
SCHEMBL19342998 0.77 HSP90AA1 (0.42) HSP90AA1HTR3AKMT2APOLBHTR3E
SCHEMBL20072051 0.77 UGT2B7 (0.41) HSP90AA1UGT2B7HTR3AKMT2AHTR3E
SCHEMBL19343013 0.76 HSP90AA1 (0.45) HSP90AA1HTR3AHTR3EHTR3BHTR5A
SCHEMBL18905696 0.76 MGLL (0.52) KMT2APOLBMEN1RAB9ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10403827-B2 2,2′-bibenzo[D]imidazolidene compound having condensed rings at the 1-, 1′-, 3- and 3′-positions, and organic light-emitting element, display device, image information processing apparatus, lighting device, image forming apparatus and exposure unit, each containing the same CANON KABUSHIKI KAISHA (JP) 2019-09-03 US disclosed
US-20180108691-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, OPTICAL AREA SENSOR, IMAGING DEVICE, AND IMAGING APPARATUS CANON KABUSHIKI KAISHA (JP) 2018-04-19 US disclosed
US-20170263870-A1 2,2'-BIBENZO[D]IMIDAZOLIDENE COMPOUND HAVING CONDENSED RINGS AT THE 1-, 1'-, 3- AND 3'-POSITIONS, AND ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, IMAGE INFORMATION PROCESSING APPARATUS, LIGHTING DEVICE, IMAGE FORMING APPARATUS AND EXPOSURE UNIT, EACH CONTAINING THE SAME CANON KABUSHIKI KAISHA (JP) 2017-09-14 US disclosed
US-20170263870-A1 2,2'-BIBENZO[D]IMIDAZOLIDENE COMPOUND HAVING CONDENSED RINGS AT THE 1-, 1'-, 3- AND 3'-POSITIONS, AND ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, IMAGE INFORMATION PROCESSING APPARATUS, LIGHTING DEVICE, IMAGE FORMING APPARATUS AND EXPOSURE UNIT, EACH CONTAINING THE SAME CANON KABUSHIKI KAISHA (JP) 2017-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170263870-A1 2,2'-BIBENZO[D]IMIDAZOLIDENE COMPOUND HAVING CONDENSED RINGS AT THE 1-, 1'-, 3- AND 3'-POSITIONS, AND ORGANIC LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, IMAGE INFORMATION PROCESSING APPARATUS, LIGHTING DEVICE, IMAGE FORMING APPARATUS AND EXPOSURE UNIT, EACH CONTAINING THE SAME GRK1, BRD1, BRD8 HSP90AA1 2688/4885UGT2B7 683/4885HTR3A 777/4885
US-10403827-B2 2,2′-bibenzo[D]imidazolidene compound having condensed rings at the 1-, 1′-, 3- and 3′-positions, and organic light-emitting element, display device, image information processing apparatus, lighting device, image forming apparatus and exposure unit, each containing the same GRK1, BRD1, BRD8 HSP90AA1 2646/4885UGT2B7 716/4885HTR3A 767/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.