Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 6/20 | 0.36 |
| ▸ | PHGDH | O43175 | 13/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23366353 | 0.88 | SLC6A9 (0.38) | SLC6A9PHGDH | |
| SCHEMBL19343471 | 0.86 | PHGDH (0.48) | SLC6A9PHGDH | |
| SCHEMBL20793443 | 0.81 | PHGDH (0.44) | SLC6A9PHGDHCNR1 | |
| SCHEMBL26373066 | 0.80 | PHGDH (0.43) | SLC6A9PHGDH | |
| SCHEMBL20768453 | 0.80 | PHGDH (0.48) | SLC6A9PHGDH | |
| SCHEMBL19343374 | 0.78 | PHGDH (0.51) | SLC6A9PHGDHCNR1CNR2 | |
| SCHEMBL24872871 | 0.76 | PHGDH (0.41) | PHGDH | |
| SCHEMBL23366425 | 0.73 | PHGDH (0.36) | SLC6A9PHGDH | |
| SCHEMBL19343240 | 0.73 | PHGDH (0.51) | SLC6A9PHGDH | |
| SCHEMBL19343475 | 0.73 | PHGDH (0.50) | SLC6A9PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3884939-B1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS INC (US) | 2023-10-25 | — | — | EP | disclosed |
| WO-2017156165-A1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |