Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 5/20 | 0.38 |
| ▸ | PHGDH | O43175 | 14/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20793443 | 0.93 | PHGDH (0.44) | SLC6A9PHGDH | |
| SCHEMBL19343474 | 0.88 | SLC6A9 (0.36) | SLC6A9PHGDH | |
| SCHEMBL19343240 | 0.85 | PHGDH (0.51) | SLC6A9PHGDH | |
| SCHEMBL23366425 | 0.85 | PHGDH (0.36) | SLC6A9PHGDHOPRM1OPRL1 | |
| SCHEMBL19331421 | 0.79 | PHGDH (0.61) | SLC6A9PHGDH | |
| SCHEMBL19343488 | 0.78 | PHGDH (0.51) | SLC6A9PHGDH | |
| SCHEMBL26373359 | 0.78 | PHGDH (0.42) | SLC6A9PHGDH | |
| SCHEMBL19343381 | 0.76 | PHGDH (0.43) | SLC6A9PHGDH | |
| SCHEMBL19343445 | 0.76 | PHGDH (0.51) | SLC6A9PHGDH | |
| SCHEMBL19343475 | 0.75 | PHGDH (0.50) | SLC6A9PHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3426243-B1 | 3-PHOSPHOGLYCERATE DEHYDROGENASE INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS INC (US) | 2021-05-19 | — | — | EP | disclosed |