SCHEMBL19345008

SCHEMBL19345008

N#Cc1cc(N2c3ccccc3C(c3ccccc3)(c3ccccc3)c3ccccc32)ccc1-c1ccc(N2c3ccccc3C(c3ccccc3)(c3ccccc3)c3ccccc32)cc1C#N

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
AR P10275 5/20 0.34
LMNA P02545 2/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
PGR P06401 1/20 0.33
DRD2 P14416 1/20 0.31
DRD4 P21917 1/20 0.31
DRD3 P35462 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19344965 0.89 AR (0.37) ARLMNAALDH1A1HPGDMAPK1
SCHEMBL19345013 0.87 PGR (0.36) ARLMNAALDH1A1HPGDMAPK1
SCHEMBL19340283 0.86 ITGB2 (0.33) ARLMNAALDH1A1HPGDMAPK1
SCHEMBL19345000 0.84 STS (0.39) PGR
SCHEMBL19345274 0.83 PGR (0.43) ARPGR
SCHEMBL13143204 0.80 PGR (0.45) LMNAPGR
SCHEMBL20353203 0.79 OPRM1 (0.37) LMNAALDH1A1SMN1; SMN2DRD2DRD4
SCHEMBL19345074 0.79 PGR (0.39) ARLMNAALDH1A1HPGDMAPK1
SCHEMBL18411319 0.79 AR (0.33) ARLMNAALDH1A1HPGDMAPK1
SCHEMBL19344954 0.78 TSHR (0.34) LMNASMN1; SMN2PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170263871-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2017-09-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170263871-A1 ORGANIC ELECTROLUMINESCENT MATERIAL AND ORGANIC OPTOELECTRONIC DEVICE OR10J3, RPS10, OR51E2 AR 667/4885LMNA 1723/4885ALDH1A1 616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.