Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 14/20 | 0.42 |
| ▸ | CTSS | P25774 | 9/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19345927 | 0.85 | CAPN1 (0.39) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL8951268 | 0.84 | CTSK (0.48) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL19346052 | 0.84 | TDP1 (0.39) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL19345914 | 0.83 | CA1 (0.46) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL13223277 | 0.83 | CA1 (0.46) | CA1CA2CA7CTSKCTSS | |
| Hydrochloric Acid SCHEMBL9218636 | 0.83 | CTSK (0.47) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL26531724 | 0.83 | CA1 (0.53) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL7733585 | 0.82 | CTSK (0.50) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL29458939 | 0.82 | CA1 (0.45) | CA1CA2CA7CTSKCTSS | |
| SCHEMBL13223280 | 0.80 | CAPN1 (0.43) | CA1CA2CA7CTSKCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017156071-A1 | CYCLIC KETO-AMIDE COMPOUNDS AS CALPAIN MODULATORS AND METHODS OF PRODUCTION AND USE THEREOF | BLADE THERAPEUTICS, INC. (US) | 2017-09-14 | — | — | WO | disclosed |