Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 2/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | CA4 | P22748 | 6/20 | 0.55 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL7997152 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL538792 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL9135671 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL11307248 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL285297 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL15420047 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL11316678 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL7504887 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL9481330 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 | |
| Bicarbonate SCHEMBL10592361 | 1.00 | CA1 (0.56) | CA1CA2CA9CA4FAHD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104674323-B | A kind of electrophoresis colors in technique | 深圳市鑫王牌科技发展有限公司 | 2017-03-01 | — | — | CN | claimed |
| CN-104674323-A | Electrophoretic color filling process | SHENZHEN XIN KINGBRAND TECHNOLOGY DEV CO LTD | 2015-06-03 | — | — | CN | claimed |
| CN-104475267-A | Galena collecting agent and preparation method thereof | NORTHWEAT RES INST OF MINING & METALLURG INST | 2015-04-01 | — | — | CN | claimed |
| CN-102716849-B | Protection method applied to aluminum alloy in vanadium battery solution | INST METAL RES CHINESE ACAD SC | 2013-12-11 | — | — | CN | claimed |
| CN-1600102-A | Bactericin agent of trichloro-isocyanuric acid | BEIFANG CHLORIDE & ALKALI GROU (CN) | 2005-03-30 | — | — | CN | claimed |
| US-9765453-B2 | Spinning, cheese dyeing, knitting and weaving process of a high performance flame-resistant modacrylic/cotton safety apparel fabric | GUANGDONG KINGTIDE DEVELOPMENT CO., LTD. (CN) | 2017-09-19 | — | — | US | disclosed |
| CN-106822024-A | A kind of effervescent tablet for treating sphagitis and its application | 江阴市本特塞缪森生命科学研究院有限公司 | 2017-06-13 | — | — | CN | disclosed |
| CN-104674323-B | A kind of electrophoresis colors in technique | 深圳市鑫王牌科技发展有限公司 | 2017-03-01 | — | — | CN | disclosed |
| CN-105969545-A | Aircraft engine cleansing agent and preparing method thereof | 北京科宇泰技术开发有限公司 | 2016-09-28 | — | — | CN | disclosed |
| CN-104674323-A | Electrophoretic color filling process | SHENZHEN XIN KINGBRAND TECHNOLOGY DEV CO LTD | 2015-06-03 | — | — | CN | disclosed |
| CN-104475267-A | Galena collecting agent and preparation method thereof | NORTHWEAT RES INST OF MINING & METALLURG INST | 2015-04-01 | — | — | CN | disclosed |
| CN-1600102-A | Bactericin agent of trichloro-isocyanuric acid | BEIFANG CHLORIDE & ALKALI GROU (CN) | 2005-03-30 | — | — | CN | disclosed |