Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.61 |
| ▸ | ACHE | P22303 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17241776 | 1.00 | BCHE (0.61) | BCHEACHELMNAPSEN1PSEN2 | |
| SCHEMBL17241765 | 1.00 | BCHE (0.61) | BCHEACHELMNAPSEN1PSEN2 | |
| SCHEMBL19553795 | 0.87 | BCHE (0.48) | BCHEACHELMNAPSEN1PSEN2 | |
| SCHEMBL6251358 | 0.78 | BCHE (0.94) | BCHEACHELMNAPDPK1MTOR | |
| SCHEMBL8715956 | 0.78 | BCHE (0.94) | BCHEACHELMNAPDPK1MTOR | |
| SCHEMBL8715953 | 0.78 | BCHE (0.94) | BCHEACHELMNAPDPK1MTOR | |
| SCHEMBL12164680 | 0.78 | BCHE (0.94) | BCHEACHELMNAPDPK1MTOR | |
| SCHEMBL10444884 | 0.78 | BCHE (0.94) | BCHEACHELMNAPDPK1MTOR | |
| Ammonia Solution, Strong SCHEMBL10444883 | 0.77 | BCHE (0.92) | BCHEACHELMNAPDPK1MTOR | |
| Ammonia Solution, Strong SCHEMBL9348688 | 0.77 | BCHE (0.92) | BCHEACHELMNAPDPK1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9834515-B2 | Process for synthesis of piperidine alkaloids | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-12-05 | — | — | US | disclosed |
| US-20170267636-A1 | A PROCESS FOR SYNTHESIS OF PIPERIDINE ALKALOIDS | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2017-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170267636-A1 | A PROCESS FOR SYNTHESIS OF PIPERIDINE ALKALOIDS | GALE, PNMT, DPM1 | BCHE 422/4885ACHE 1023/4885LMNA 3024/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.