Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HK1 | P19367 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.42 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | CCKAR | P32238 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDO2 | P48775 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19348411 | 0.92 | ALDH1A1 (0.44) | ALDH1A1LMNAMAPTHK1HKDC1 | |
| SCHEMBL19348493 | 0.90 | PTGDR2 (0.52) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL19361482 | 0.87 | PTGDR2 (0.51) | PTGDR2TBXA2RPTGDRCYP2C9 | |
| SCHEMBL19368926 | 0.86 | PTGDR2 (0.50) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL19349023 | 0.85 | MAPT (0.43) | ALDH1A1LMNAMAPTHK1HKDC1 | |
| SCHEMBL19368938 | 0.83 | ALDH1A1 (0.47) | ALDH1A1LMNAMAPTHK1HKDC1 | |
| SCHEMBL19348384 | 0.83 | ALDH1A1 (0.50) | ALDH1A1LMNAMAPTHK1HKDC1 | |
| SCHEMBL19348523 | 0.83 | PTGDR2 (0.47) | ALDH1A1LMNAMAPTHK1HKDC1 | |
| SCHEMBL19348428 | 0.82 | PTGDR2 (0.53) | PTGDR2TBXA2RPTGDRABCB11CYP2C9 | |
| SCHEMBL19361488 | 0.82 | ADORA3 (0.38) | MAPTPTGDR2TBXA2RPTGDRABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3191483-B1 | COMPOUNDS AS CRTH2 ANTAGONIST AND USES THEREOF | NORTH & SOUTH BROTHER PHARMACY INVESTMENT CO LTD (CN) | 2020-06-10 | — | — | EP | disclosed |
| US-9951010-B2 | Compounds as CRTH2 antagonist and uses thereof | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2018-04-24 | — | — | US | disclosed |
| US-20170267634-A1 | COMPOUNDS AS CRTH2 ANTAGONIST AND USES THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2017-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170267634-A1 | COMPOUNDS AS CRTH2 ANTAGONIST AND USES THEREOF | HRH2, PTGDR2, HRH1 | ALDH1A1 1226/4885LMNA 4062/4885MAPT 4097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.