Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN3 | Q9UGI6 | 14/20 | 0.58 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.58 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 0.58 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.54 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CDK9 | P50750 | 2/20 | 0.38 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.38 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CCND1 | P24385 | 1/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2029206 | 0.81 | KCNN3 (0.48) | KCNN3KCNN1KCNN2PDE10A | |
| SCHEMBL14158199 | 0.78 | PDE10A (0.61) | KCNN3KCNN1KCNN2PDE10APRKAB2 | |
| SCHEMBL11568710 | 0.78 | PIK3CD (0.37) | KCNN3KCNN1KCNN2CCNT1CDK2 | |
| SCHEMBL5447969 | 0.76 | KCNN3 (0.66) | KCNN3KCNN1KCNN2PDE10APRKAB2 | |
| SCHEMBL14158215 | 0.74 | KCNN3 (0.71) | KCNN3KCNN1KCNN2PDE10ACCNT1 | |
| SCHEMBL31602186 | 0.73 | KCNN3 (0.46) | KCNN3KCNN1KCNN2PDE10ACDK2 | |
| SCHEMBL31602093 | 0.73 | KCNN3 (0.41) | KCNN3KCNN1KCNN2PDE10A | |
| SCHEMBL1934455 | 0.73 | KCNN3 (0.43) | KCNN3KCNN1KCNN2PDE10ACCNT1 | |
| SCHEMBL1487772 | 0.73 | CDK9 (0.58) | KCNN3KCNN1KCNN2PDE10ACCNT1 | |
| SCHEMBL13998582 | 0.73 | KCNN3 (0.55) | KCNN3KCNN1KCNN2PDE10ACDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509602-A1 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | Cylene Pharmaceuticals, Inc. (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011068667-A1 | PYRAZOLOPYRIMIDINES AND RELATED HETEROCYCLES AS CK2 INHIBITORS | CYLENE PHARMACEUTICALS, INC. (US) | 2011-06-09 | — | — | WO | disclosed |